Beauty in 2 hours or less—order online, pick up in store.

Use the following zoom and pan buttons to control the image that follows them

Differin Epiduo Acne Treatment Gel #1
Differin Epiduo Acne Treatment Gel #1

 Epiduo Acne Treatment Gel

$24.99

or

Size:0.53 oz

Pickup and delivery options

In stock and ready to ship

Usually ships in 24 hours

Save 5% on your first subscription order, then 5% on every recurring order. Enjoy free shipping and cancel anytime!

Earn points on this purchase.

Details

Benefits

  • The first clinically proven dual active formula with benzoyl peroxide & retinoid adapalene to clear and prevent acne
  • Treats acne to improve skin tone, texture & radiance and prevents acne from coming back
  • Starts killing acne causing bacteria from day 1 with consistently clearer skin overtime

Key Ingredients

  • Adapalene 0.1%
  • Benzoyl Peroxide 2.5%

Item 2656239

How To Use

Adults and children 12 years of age and older: Use once daily. Clean the skin gently and pat dry before applying the product. Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. Do not use more than one time a day.

Precautions: Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor. If pregnant or breast feeding, ask a doctor before use. Do not use Differin Gel if you are allergic to adapalene, benzoyl peroxide or any of the ingredients in the product.

Ingredients

Active: Adapalene 0.1%, Benzoyl Peroxide 2.5%.

Inactive: Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Docusate Sodium, Edetate Disodium, Glycerin, Isohexadecane, Poloxamer 124, Polysorbate 80, Propylene Glycol, Purified Water, Sorbitan Oleate.

Frequently bought together

3 items

Current Product

Differin

Epiduo Acne Treatment Gel

Size

0.53 oz

$24.99

Make it a routine

Add these personalized recommendations to complete your beauty routine.

Step 1

Step 2

Current Product

Differin

Epiduo Acne Treatment Gel

Size:

0.53 oz

$24.99

Step 3

Similar items for you

12 items

We think you'll like

12 items

Sponsored products

12 items

Review Snapshot

by PowerReviews

606 ReviewsWrite a Review
91%
of respondents would recommend this to a friend
Ratings Distribution
Pros
No Pros
Cons
No Cons
Most Helpful Positive Review
My skin looks calmer and not as congested.

[I received this product in exchange for my honest review] After 4 weeks I noticed fewer active breakouts & less overall congestion especially across my cheeks! I was dedicating myself to this product so much I only wore makeup once just because my skin is more acne prone and I wanted to prevent any...

Versus
Most Helpful Critical Review
Terrible product will not be buying again

I bought this product to help me with my pimples, and it was the worst decision I made. My skin is very flaky and very painful to the touch. I can't use any kind of moisturizer to help through the pain. It definitely burned my face and peeled off my skin, I tried moisturizer, but it didn't work. I w...

606 results

Not for easily irritated or sensitive skin

Submitted 1 month ago

By Zaire

From Newark, New Jersey

[I received this product in exchange for my honest review] Use the product for 3 months now. Although my skin's integrity has greatly improved, I would not go out of my way to purchase this product. I used it throughout the summer and I am out in the sun often. While I used spf, I still did not like how my skin felt when returning home. I would not recommend this for people with sensitive skin regardless if you use spf to protect yourself. My skin also looks the same acne wise even with the usage. It's an okay product. It feels great and lasts long if used properly as I still have a bit left.

User submitted media
Top: Before (July, 1, 2026) | Bottom: After (October 3, 2026)

Bottom Line No, I would not recommend to a friend

Was this review helpful to you?
Not for irritated or sensitiveskin

Submitted 1 month ago

By ZaireR

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Differin - BV

Use the product for 3 months now. Although my skin's integrity has greatly improved, I would not go out of my way to purchase this product. I used it throughout the summer and I am out in the sun often. While I used spf, I still did not like how my skin felt when returning home. I would not recommend this for people with sensitive skin regardless if you use spf to protect yourself. My skin also looks the same acne wise even with the usage. It's an okay product. It feels great and lasts long if used properly as I still have a bit left.

Was this review helpful to you?
I've used the old dark...

Submitted 1 month ago

By Nikiered42

From undisclosed

Verified Reviewer

Reviewed at

Differin - BV

I've used the old dark spot treatment and it worked perfectly this new stuff has burnt my face made a rash and it irritation severely I do not like this new stuff

Was this review helpful to you?
my skin feels smoother and clearer

Submitted 1 month ago

By leslie

From Houston, TX

[I received this product in exchange for my honest review] my skin feels smoother and clearer, with noticeable improvement in my acne and dark spots. it's been a great addition to my skin care routine for the past couple of weeks!

User submitted media
skin improvement

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
my skin feels smoother and clearer

Submitted 1 month ago

By LeslieC

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Differin - BV

my skin feels smoother and clearer, with noticeable improvement in my acne and dark spots. it's been a great addition to my skin care routine for the past couple of weeks!

Was this review helpful to you?