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Perricone MD Neuropeptide Deep Crease Serum #1
Perricone MD Neuropeptide Deep Crease Serum #1

Perricone MD Neuropeptide Deep Crease Serum

$189.00
Size:3.4 oz

Pickup and delivery options

In stock and ready to ship

Details

Benefits

  • This highly-potent, silky serum smooths the look of even the most stubborn, deep lines, wrinkles & creases around the mouth, eyes, lips & forehead, including marionette lines, frown lines, smile lines & nasolabial folds
  • Over time, wrinkle depth appears shallower & the look of expression lines reduced

Key Ingredients

  • Neuropeptides: Uniting Surface Cells to Fight Wrinkles
  • Biomimetic Growth Factor Peptides
  • Plant Stem Cells

Item 2648227

How To Use

After cleansing, massage onto face & neck using a gentle upward motion. Wait until fully absorbed & follow with your favorite Perricone MD moisturizer. Use morning & evening.

If the product enters the eye, rinse with water to remove.

Ingredients

Water/Aqua/Eau, Niacinamide, Coconut Alkanes, Glycerin, Caprylic/Capric Triglyceride, Isodecyl Neopentanoate, Squalane, Isononyl Isononanoate, Butylene Glycol, Lactobacillus/Glycine Soybean Ferment Extract, Polyglutamic Acid, Phenoxyethanol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Chlorella Vulgaris Extract, Glyceryl Stearate Citrate, Coco-Caprylate/Caprate, Hydroxyacetophenone, Polyglyceryl-3 Stearate, Hydrolyzed Rice Protein, Sodium Hyaluronate, Propanediol, Xanthan Gum, Pullulan, Hydrogenated Lecithin, Fragrance (Parfum), Polysorbate 60, Citric Acid, Sodium Phytate, Malus Domestica Fruit Cell Culture Extract, Sorbitan Isostearate, Glyceryl Stearate, Pentylene Glycol, Carbomer, Ceteareth-25, Coco-Glucoside, Sodium Lactate, Ubiquinone, Lecithin, Sodium Benzoate, Potassium Sorbate, Caprylyl Glycol, Acetyl Hexapeptide-8, Ceteareth-6, Lactic Acid, Pterocarpus Marsupium Bark Extract, Tocopherol, Stearyl Alcohol, Acetic Acid, Ethylhexylglycerin, Palmitoyl Tripeptide-1, Sodium Hydroxide, Palmitoyl Tetrapeptide-7, Nicotiana Benthamiana Hexapeptide-40 SH-Oligopeptide-1, Nicotiana Benthamiana Octapeptide-30 SH-Oligopeptide-2, Citronellol, Hydroxycitronellal, Limonene, Linalool.

Shipping & Coupon Restrictions

This brand is excluded from most Ulta Beauty coupons.

See brand eligibility details

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NEUROPEPTIDE DEEP CREASE SERUM

NEW: NEUROPEPTIDE DEEP CREASE SERUM

DISCONTINUED: ESSENTIAL FX DEEP CREASE SERUM

DISCONTINUED: ESSENTIAL FX DEEP CREASE SERUM

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Essential FX Deep Crease Serum Features & Benefits

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Targets:

  • Deep Wrinkles
  • Creases
  • Expression Lines
  • Crepiness
  • Loss of Smoothness

Targets:

  • Fine Lines & Wrinkles
  • Loss of Firmness
  • Loss of Volume
  • Uneven Texture
  • Uneven Tone

Targets:

  • Dehydration
  • Dryness
  • Fine Lines & Wrinkles
  • Loss of Volume
  • Loss of Radiance

Targets:

  • Discoloration
  • Uneven Tone
  • Redness
  • Loss of Radiance
  • Loss of Elasticity
  • Lines & Wrinkles

Targets:

  • Loss of Radiance
  • Redness
  • Uneven Tone

Advanced Hydrating Complex

Cold Plasma Plus+ Advanced Hydrating Complex

Retinol Recovery Overnight Moisturizer

​Retinol Recovery Overnight Moisturizer

High Potency Hyaluronic Intensive Mositurizer

​Hyaluronic Intensive Moisturizer

Vitamin C Ester Photo-Brightening Moisturizer

Vitemin C Ester Photo-Brightening Moistruizer SPF 30

High Potency Hyaluronic Intensive Mositurizer

Hyaluronic Intensive Moisturizer

What do you want to know about this product?

Review Snapshot

by PowerReviews

121 ReviewsWrite a Review
Ratings Distribution
Pros
No Pros
Cons
No Cons
Most Helpful Positive Review
Botox Alternative? For SOFTENING creases trying Pe

At 42, I'm at the point where my forehead wrinkles are becoming a permanent, prominent feature, and I'm desperately trying to avoid the injectable route! I'm looking for a serious solution that can deliver noticeable results without a trip to the dermatologist, which is why I was so excited to incor...

Versus
Most Helpful Critical Review
It's ok

Been using this product for about a week--I think it could've used a longer test time and I also don't believe that a before/after photo would do the best at demonstrating its efficacy, since skincare rarely makes a dramatic enough impact to be perceptible on camera. But all the same, if that's what...

121 results

Smooth

Submitted 4 months ago

By mayras57_8897

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Perricone MD - BV

So happy with how this has helped around my eyes. I use it both day and night before applying my moisturizer. The texture is thick, but still goes on smooth and creamy.

Was this review helpful to you?
Smoother Skin, Real Results!

Submitted 4 months ago

By erikao108_2009

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Perricone MD - BV

I've been using Perricone MD Neuropeptide Deep Crease Serum for a few weeks, and I can honestly see a difference. My fine lines look softer, and my skin feels firmer and smoother. It absorbs quickly and layers well under moisturizer or makeup. It's definitely a splurge, but the results make it worth it—I feel like my skin looks more refreshed and youthful every day!

Was this review helpful to you?
Awesome skin care product!

Submitted 4 months ago

By nieshar1_2661

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Perricone MD - BV

The packaging came wrapped good, This is a good product,The texture ,effectiveness,scent and it absorption is well. This is a very good product to use on your skin.

Was this review helpful to you?
Love it!

Submitted 4 months ago

By kellie8_5580

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Perricone MD - BV

My new favorite wrinkle cream! I love the way it smells. I love the way it Blends into my skin nicely. I can tell that it is working on my forehead and the Deep lines I have there. The packaging also is very Lux

Was this review helpful to you?
Smooth, light and Worth it! 🫶🏼

Submitted 4 months ago

By denicet4_2310

From undisclosed

Verified Reviewer

Submitted as part of a sweepstakes entry

Reviewed at

Perricone MD - BV

I have sensitive skin that can range from dry to oily, and I'm so grateful this serum didn't cause any breakouts or irritation to my skin. The texture is super soft, not sticky at all, and absorbs beautifully into the skin. I've been using it for the past few weeks and have definitely noticed a difference. The deep crease lines around my smile and neck are visibly smoother. There's also really no smell, nor perfumes to it. Consistency really matters with this product. sticking to your morning and night routine makes all the difference if you want to see real results. I'm really happy with how my skin looks and feels!

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