SKIP TO MAINSKIP TO FOOTER

Free standard shipping on any $35 purchase

Use the following zoom and pan buttons to control the image that follows them

Perricone MD High Potency Hyaluronic Intensive Hydrating Serum #1
Perricone MD High Potency Hyaluronic Intensive Hydrating Serum #1

Tab through the images or use the previous or next buttons to navigate each product image

Perricone MD High Potency Hyaluronic Intensive Hydrating Serum

Sale

sale price $81.00regularly $135.00

Replenish & Save

Size:2.0 oz

Pickup and delivery options

In stock and ready to ship

Save 5% and get free shipping on each subscription order. Cancel anytime!

Earn points on this purchase.

Details

Features

  • This deeply nourishing serum is designed with 4 forms and 2 natural building blocks of hyaluronic acid to instantly replenish with essential moisture for visibly smoother, firmer and plumper skin
  • This fast-absorbing formula helps strengthen skin's moisture barrier, increase the feel of skin cushion and reduce the appearance of fine lines and wrinkles for a healthy, youthful-looking appearance. Leaves skin looking and feeling soft, supple and rejuvenated
  • Helps dryness and dehydration, and loss of radiance, loss of volume, fine lines and wrinkles

Key Ingredients

  • Hyaluronic 4 + 2 Complex: Instant & Long-Lasting Hydration
  • DMAE: Intensive Firming
  • Niacinamide: Visibly Renews & Restores

Research Results

  • 97% showed improvement in skin hydration for 72 hours*
  • 80% showed improvement in skin barrier function after 8 weeks*
  • *In a clinical study of 35 women.

Item 2595124

How To Use

After cleansing, massage onto damp face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.

Ingredients

Water/Aqua/Eau, Dimethicone, Butylene Glycol, Niacinamide, Acetyl Glucosamine, Squalane, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysilicone-11, Cetearyl Olivate, HDI/Trimethylol Hexyllactone Crosspolymer, Polyisobutene, Sorbitan Olivate, Dimethyl Isosorbide, Polysorbate 20, 1,2-Hexanediol, Caprylyl Glycol, Dimethyl MEA, Hydroxyacetophenone, Citric Acid, Ceramide NP, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Sodium Gluconate, Spermidine, Silica, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Phenoxyethanol, Phytosphingosine, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Ethylhexylglycerin, Acetyl Tetrapeptide-11, Acetyl Tetrapeptide-9, Glycerin, Disodium Acetyl Glucosamine Phosphate, Sodium Glucuronate, Magnesium Sulfate.

Shipping & Coupon Restrictions

This brand is excluded from most Ulta Beauty coupons.

See brand eligibility details

Make it a routine

Add these personalized recommendations to complete your beauty routine.

Step 1

La Roche-Posay

Toleriane Purifying Foaming Face Wash for Oily Skin

Size:: 13.5 oz
$21.99

Step 2

Current Product

Perricone MD

High Potency Hyaluronic Intensive Hydrating Serum

Step 3

Clinique

Moisture Surge 100H Auto-Replenishing Hydrator Gel Moisturizer with Hyaluronic Acid

Size:: 4.2 oz
$88.00

Sponsored products

12 items

Powered by syndigo
Hydration Insider
Immediate, Deep Hydration

IMMEDIATE, DEEP HYDRATION

This potent serum intensely replenishes essential moisture while protecting the skin's moisture barrier and reducing the look of fine lines and wrinkles for a visibly smoother, firmer, and plumper look

EXCLUSIVE HYALURONIC ACID TECHNOLOGY

Our proprietary hyaluronic acid complex features 4 forms and 2 natural building blocks of this essential ingredient to deeply hydrate for smoother and plumper-looking skin

RESULTS YOU CAN SEE

RESULTS YOU CAN SEE

97% saw improved hydration for 72 hours*


86% saw softened fine lines & wrinkles**


85% felt firmer, more supple skin*


*In a clinical study of 33 women

** In a consumer study of 109 women after 28 days







Find Your Best Serum

Product Comparison

This Product

High Potency Hyaluronic Intensive Hydrating Serum

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin Types

AM & PM 

AM & PM

AM & PM

AM & PM

AM & PM

AM & PM

AM & PM

Hyaluronic Intensive Hydrating Serum Smear

Lightweight, Gel Serum

Advanced Serum Concentrate Smear

Lightweight Serum

Triple Retinol Renewal Serum Smear

Lightweight, Serum

Deep Crease Serum Smear

Lightweight, Serum

Vitamin C Ester CCC + Ferulic Brightening Complex 20% Smear

Lightweight, Serum

Vitamin C Ester Brightening Serum Smear

Lightweight, Serum

Intensive Smoothing Serum Smear

Lightweight, Silky Serum

Targets:

  • Dehydration
  • Dryness
  • Fine Lines & Wrinkles
  • Loss of Volume
  • Loss of Radiance
  • Targets:
  • Fine Lines
  • Wrinkles
  • Enlarged Pores
  • Loss of Firmness
  • Redness
  • Dullness
  • Uneven Tone
  • Uneven Texture
  • Discoloration
  • Targets:
  • Fine Lines & Wrinkles
  • Loss of Firmness
  • Loss of Volume
  • Uneven Texture
  • Uneven Tone
  • Targets:
  • Deep Wrinkles
  • Creases
  • Expression Lines
  • Crepiness
  • Loss of Smoothness
  • Targets:
  • Discoloration
  • Uneven Tone
  • Redness
  • Loss of Radiance
  • Loss of Elasticity
  • Lines & Wrinkles
  • Targets:
  • Loss of Radiance
  • Redness
  • Uneven Tone
  • Targets:
  • Rough Texture
  • Enlarged Pores
  • Fine Lines & Wrinkles
  • Loss of Smoothness
  • Uneven Tone
  • Loss of Clarity
  • Loss of Firmness

Retinol Recovery Overnight Moisturizer

High Potency Retinol Recovery Overnight Moisturizer

Advanced Hydrating Complex

Cold Plasma Plus+ Advanced Hydrating Complex

High Potency Hyaluronic Intensive Mositurizer

High Potency Hyaluronic Intensive Moisturizer

Advanced Hydrating Complex

Cold Plasma Plus+Advanced Hydrating Complex

High Potency Face Finishing & Firming Moisturizer

High Potency Face Finishing & Firming Moisturizer

High Potency Hyaluronic Intensive Mositurizer

High Potency Hyaluronic Intensive Moisturizer

Retinol Recovery Overnight Moisturizer

High Potency Retinol Recovery Overnight Moisturizer

Q&A

Showing 2 out of 2 Questions
Q
Where is this product made?
Asked by Tantan
Official Answer By Perricone MD - Brand Engage
The High Potency Hyaluronic Intensive Hydrating Serum is made in the USA.Was this answer helpful to you
Q
What is the shelf life/exp date for this product?
Asked by CB
Official Answer By Perricone MD - Brand Engage
The shelf life for this product is 12 months after opening.Was this answer helpful to you

Review Snapshot

by PowerReviews

862 ReviewsWrite a Review
97%
of respondents would recommend this to a friend
Ratings Distribution
Pros
Cons
Best Uses
Describe Yourself
Skin Type
Most Helpful Positive Review
Best face serum I've tried in years.

This face serum is the best I've tried in years. I have a very sensitive skin. I have to deal with Rosacea!. This serum hydrates my skin for 24h. Makes the skin so soft. It calms down my skin. Reduced redness...... Amazing serum. I use it two times a day. I highly recommend it.

Versus
Most Helpful Critical Review
Wish my skin didn't have a reaction to it because I loved it

#sponsored #perriconeinsider I was kindly gifted the Perricone MD High Potency Hyaluronic Intensive Hydrating Serum from @bzzagent and @perriconemd in exchange for an honest review This serum is designed with 4 forms and 2 natural building blocks of hyaluronic acid to instantly replenish with essen...

862 results

Insanely priced serum that pills and rubs off

Submitted 2 months ago

By RDee

From PA

(I just spent a while writing a more in depth review on this product, sumbitted it, and the Ulta app said there was an error.) To sum up my previous review, I recieved a sample of this one Christmas and was beyond impressed by it. For reference, I buy high and low priced skincare and makeup products--I'm always on the search of what works best for me (and I have cheap and exprensive holy grail products). That being said, I think it might be the most I've spent on a skincare product. That wouldnt have phased me if this product didn't turn out to be AWFUL! Now to the point, I have tried this product by itself, layered under and over many different products. I've tried this serum so many times. Ultimately, it immediately PILLS everytime I apply it. Then I have to take a dry washcloth and wipe the dried pills off. I'm not sure why I gave this product so many chances (probably the price point). It is obviously going into the garbage today! I am overall very disappointed by this product and brand.

Was this review helpful to you?
I never break out but....

Submitted 5 months ago

By Ems

From FL

This product went on very smoothly and my skin felt very hydrated almost immediately after application. Unfortunately when I woke up the next morning both sides of my face were covered in pimples/rash. I never break out with products as my skin is not sensitive therefore something in this product definitely didn't agree with me and I would never try it again.

Was this review helpful to you?
I'm buying it over and over!

Submitted 10 months ago

By Julie

From Park city, utah

I received this as a sample, I didn't know what it was, I just put it on and omg it worked so good. It reduced my redness and I had such a youthful face. I loved it so much I looked it up and realize how expensive it was but with the difference I had noticed, I bought it!

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
not worth this ridiculous price

Submitted 1 year ago

By Agnes

From Boston, MA

Mild hydration and that's it. You can buy similar product for at least half the price!

Was this review helpful to you?
Gives a boost of hydration.

Submitted 1 year ago

By Divamum

From Washington DC

Reviewed at

Perricone MD US

I use this whenever I need a bit of extra hydration. Plays well with all products. Always have a bottle on hand.

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?