SKIP TO MAINSKIP TO FOOTER

Free standard shipping on any $35 purchase

Use the following zoom and pan buttons to control the image that follows them

Perricone MD High Potency Triple Retinol Renewal Serum #1
Perricone MD High Potency Triple Retinol Renewal Serum #1

Tab through the images or use the previous or next buttons to navigate each product image

Perricone MD High Potency Triple Retinol Renewal Serum

Sale

sale price $81.00regularly $135.00

Replenish & Save

Size:2.0 oz

Pickup and delivery options

In stock and ready to ship

Save 5% and get free shipping on each subscription order. Cancel anytime!

Earn points on this purchase.

Details

Benefits

  • Formulated with a proprietary triple retinol blend, this powerful day & night serum accelerates skin renewal with less sensitivity to deliver the look of collagen-rich, firmer skin
  • Works together with antioxidant powerhouse coenzyme Q10, & naturally derived beta-carotene (vitamin A) to visibly diminish uneven texture & dullness for a more even, radiant complexion

Key Ingredients

  • Triple Retinol Blend: Advanced Skin Recovery
  • Coenzyme Q10 (CoQ10): Antioxidant Skin Renewal
  • Beta-Carotene Anti-Photoaging Support:

Research Results

  • 93% agreed it does not cause any visible signs of irritation, such as redness, scaling, swelling††
  • 91% agreed it does not cause any skin discomfort, such as stinging, burning, itching, tightness††
  • 86% agreed skin texture looks and feels smoother††
  • 78% showed significant improvement in the feel of rough skin texture**
  • **In a clinical study of 37 women after 8 weeks.
  • ††In a consumer study of 102 women after 28 days.

Item 2632048

How To Use

After cleansing, massage onto face & neck using a gentle upward motion. Use morning & evening. If used in the morning, follow with SPF. This product contains Vitamin A. Do not use if pregnant or breastfeeding. Use with caution if also taking dietary supplements or using other products containing Vitamin A.

Ingredients

Water/Aqua/Eau, Glycerin, Dimethicone, Propanediol, Squalane, Butylene Glycol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Niacinamide, Rubus Idaeus (Raspberry) Seed Oil, Lactobacillus Ferment, Phenoxyethanol, Polyacrylate Crosspolymer-6, Pentylene Glycol, Caprylic/Capric Triglyceride, Ethylhexylglycerin, Linum Usitatissimum (Linseed) Seed Extract, Tetrasodium Glutamate Diacetate, Mannose, Sodium Mannose Phosphate, Ceramide NP, Allantoin, Aloe Barbadensis Leaf, Bisabolol, Retinol, Polysorbate 20, Lecithin, Polysorbate 60, Sorbitan Isostearate, Chlorella Vulgaris Extract, Hydrogenated Phosphatidylcholine, Lysolecithin, Retinyl Linoleate, Hydroxyphenyl Propamidobenzoic Acid, Cetyl Palmitate, Laureth-23, Sodium Hyaluronate Cross-polymer, Tocopheryl Acetate, Glyceryl Caprylate, P-Anisic Acid, Glycine Soja (Soybean) Oil, Sodium Hydroxide, Sodium Hyaluronate, Thioctic Acid, Trideceth-6 Phosphate, Sodium Acetylated Hyaluronate, Ubiquinone, Tocopherol, Citric Acid, Hyaluronic Acid, Hydrolyzed Glycosaminoglycans, Hydrolyzed Sodium Hyaluronate, 1,2-Hexanediol, Lactic Acid, Sodium Benzoate, Ascorbyl Palmitate, Potassium Sorbate, Hydrolyzed Hyaluronic Acid, Beta Carotene,Daucus Carota Sativa (Carrot) Root Extract, Phytic Acid, Caprylhydroxamic Acid, Beta-Sitosterol, Squalene, Arginine/Lysine Polypeptide.

Shipping & Coupon Restrictions

This brand is excluded from most Ulta Beauty coupons.

See brand eligibility details

Frequently bought together

3 items

Current Product

Perricone MD

High Potency Triple Retinol Renewal Serum

OSEA

Undaria Algae Body Wash

$32.00
Perricone MD

High Potency Triple Retinol Renewal Eye Serum

Make it a routine

Add these personalized recommendations to complete your beauty routine.

Step 1

La Roche-Posay

Toleriane Hydrating Gentle Face Cleanser for Dry Skin

Size:: 13.5 oz
$21.99

Step 2

Current Product

Perricone MD

High Potency Triple Retinol Renewal Serum

Step 3

IT Cosmetics

Confidence in a Cream Anti-Aging Hydrating Moisturizer

Size:: 2.0 oz
$59.00

We think you'll like

12 items

Similar items for you

12 items

Sponsored products

12 items

Powered by syndigo
3x Retinol Power
Unmatched Benefits

UNMATCHED BENEFITS

  • Supports natural skin renewal in 3 days
  • Minimizes the look of lines and wrinkles
  • Visibly reduces redness & dullness
Results You Can See

RESULTS YOU CAN SEE

96% said it feels gentle on skin***

83% said it smooths skin texture & reduces dullness*

76% showed a reduction in fine lines*** & improvement in elasticity** & resiliency**


*In a consumer study of 102 women after 28 days.

*** In a clinical study of 37 women after 4 weeks

** After 8 weeks

POWERFUL, YET GENTLE

POWERFUL, YET GENTLE

Beta-carotene protects the concentrated retinol levels while antioxidant powerhouse coenzyme Q10 (CoQ10) simultaneously neutralizes free radicals for maximum stability and efficacy.

Find Your Best Serum

Product Comparison

This Product

Triple Retinol Renewal Serum

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin Types

All Skin TYpes

AM & PM

AM & PM

AM & PM

AM & PM

AM & PM

AM & PM

AM & PM

Triple Retinol Renewal Serum Smear

Lightweight, Serum

Advanced Serum Concentrate Smear

Lightweight, Serum

Gel-Serum

Deep Crease Serum Smear

Lightweight, Serum

Vitamin C Ester CCC + Ferulic Brightening Complex 20% Smear

Lightweight, Serum

Vitamin C Ester Brightening Serum Smear

Lightweight Serum

Intensive Smoothing Serum Smear

Lightweight, Silky Serum

Targets:

  • Fine Lines & Wrinkles
  • Loss of Firmness
  • Loss of Volume
  • Uneven Texture
  • Uneven Tone


Targets:

  • Fine Lines
  • Wrinkles
  • Enlarged Pores
  • Loss of Firmness
  • Redness
  • Dullness
  • Uneven Tone
  • Uneven Texture
  • Discoloration


Targets:

  • Dehydration
  • Dryness
  • Fine Lines & Wrinkles
  • Loss of Volume
  • Loss of Radiance

Targets:

  • Deep Wrinkles
  • Creases
  • Expression Lines
  • Crepiness
  • Loss of Smoothness


Targets:

  • Discoloration
  • Uneven Tone
  • Redness
  • Loss of Radiance
  • Loss of Elasticity
  • Lines & Wrinkles


Targets:

  • Loss of Radiance
  • Redness
  • Uneven Tone


Targets:

  • Rough Texture
  • Enlarged Pores
  • Fine Lines & Wrinkles
  • Loss of Smoothness
  • Uneven Tone
  • Loss of Clarity
  • Loss of Firmness

High Potency Hyaluronic Intensive Mositurizer

High Potency Hyaluronic Moisturizer

Advanced Hydrating Complex

Cold Plasma Plus+ Advanced Hydrating Complex

Retinol Recovery Overnight Moisturizer

High Potency Retinol Recovery Overnight Moisturizer

Advanced Hydrating Complex

Cold Plasma Plus+ Advanced Hydrating Complex

High Potency Face Finishing & Firming Moisturizer

High Potency Face Finishing & Firming Moisturizer

Cold Plasma Plus+ Advanced Hydrating Complex

Cold Plasma Plus+ Advanced Hydrating Complex

High Potency Face Finishing & Firming Moisturizer Tinted SPF 30

High Potency Face Finishing & Firming Tinted Moisturizer SPF 30

What do you want to know about this product?

Review Snapshot

by PowerReviews

483 ReviewsWrite a Review
98%
of respondents would recommend this to a friend
Ratings Distribution
Pros
No Pros
Cons
No Cons
Most Helpful Positive Review
Fabulous retinol serum! Sadly, my bottle arrived damaged.

I generally have always liked Perricone MD products. They tend to be at the vanguard of skincare science, and their products are not only effective, but also well packaged and enjoyable to use. I have been using this High Potency Triple Retinol Renewal Serum for a little over a week now. That's w...

Versus
Most Helpful Critical Review
No significant results noticed

I wouldn't say this product is revolutionary. Have used for a couple of weeks and have not noticed any visible improvements. I understand that this type of product may need a longer trial period to see results although I am probably going to stop using it since it seems to not work well with my sk...

483 results

Still hands down the best I have found

Submitted 6 days ago

By Nicole

From Charleston, SC

I have super sensitive skin, also aging skin, fair complexion that is prone to break outs. This stuff is awesome I love it.

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
Amazing

Submitted 5 months ago

By Nicole

From Charleston, SC

I have been trying to find the best retinol for my skin and I believe I have! I have been using kiehl's for a while but always seemed heavy. I have combination skin, prone to hormonal acne around my chin/mouth and nearing 50 this helps it all!

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
Such a great Serum!

Submitted 5 months ago

By Suzanne

From Boston, MA

Verified Reviewer

Submitted as part of a free sample program

Reviewed at

Perricone MD US

Perricone MD is an amazing brand with very effective products - I've bought many of them! The new High Potency Triple Retinol Serum is a beautiful product that is gentle on my skin but actually provides results! This Serum absorbs into my skin and wears well with other skincare products without "pilling". I don't have sensitive skin, but I know that sometimes Retinol can cause irritation...I have not had any skin irritation while using the Triple Retinol Serum (or any of the other Perricone MD products that I own)! I love how my skin looks after using this Serum every night for quite a few weeks! My skin looks softer, smoother, and firmer. My fine lines look diminished and softer. And, my overall skin appearance looks better, brighter, renewed, and healthier. I'm absolutely loving my skin right now! As I mentioned, I love Perricone MD products, and this new Triple Retinol Serum is now a staple in my skincare routine that I will be repurchasing. If you haven't tried Perricone MD or the new High Potency Triple Retinol Serum yet, you're missing out!

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
Be patient - this stuff works!

Submitted 9 months ago

By Ruthie

From SF Bay Area

Verified Reviewer

Submitted as part of a free sample program

Reviewed at

Perricone MD US

I use daily in the morning, after washing and before moisturizer. It softens skin and blurs lines. With consistency, you'll see the change! Gentler than prescription retin-a, it's is a keeper

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?
Pretty good

Submitted 9 months ago

By Grace

From Texas

Verified Reviewer

Submitted as part of a free sample program

Reviewed at

Perricone MD US

I utilized this product for a good 3-4 weeks before really doing a review. I did experience a bit of dryness so I scaled back and used a couple of times a week so that my face could get used to it. I took before and after pics and although I personally didn't see visible results I did get complimented on my skin by people so it was working. I have continued to use a couple times a week.

Bottom Line Yes, I would recommend to a friend

Was this review helpful to you?