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Highlights
Summary
DIFFERIN Epiduo Acne Treatment Gel is the first clinically proven dual active formula with benzoyl peroxide & retinoid adapalene to clear and prevent acne.
Benefits
- The first clinically proven dual active formula with benzoyl peroxide & retinoid adapalene to clear and prevent acne
- Treats acne to improve skin tone, texture & radiance and prevents acne from coming back
- Starts killing acne causing bacteria from day 1 with consistently clearer skin overtime
Key Ingredients
- Adapalene 0.1%
- Benzoyl Peroxide 2.5%
Item 2656240
Adults and children 12 years of age and older: Use once daily. Clean the skin gently and pat dry before applying the product. Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. Do not use more than one time a day.
Precautions: Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor. If pregnant or breast feeding, ask a doctor before use. Do not use Differin Gel if you are allergic to adapalene, benzoyl peroxide or any of the ingredients in the product.
Active: Adapalene 0.1%, Benzoyl Peroxide 2.5%.
Inactive: Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Docusate Sodium, Edetate Disodium, Glycerin, Isohexadecane, Poloxamer 124, Polysorbate 80, Propylene Glycol, Purified Water, Sorbitan Oleate.
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Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
Effective acne treatment with easy application, mild init...
I've been using Differin Epiduo Acne Gel, and overall it has been a great addition to my skincare routine. The pump packaging is convenient, hygienic, and makes it easy to dispense the right amount without wasting product. During the first couple of weeks, I experienced some mild dryness and irritat...
Most Helpful Critical Review
I saw some improvement, but it did not clear my acne
I started breaking out on my cheeks which is pretty unusual for me. Since I was already using adapalene and benzoyl peroxide separately, I was really excited to see a product that combined both ingredients. Unfortunately, it did not make as much of a difference as I'd hoped. It did reduce some of my...
181 results
The Ultimate Acne-Fighting Combo!
This combination treatment truly transformed my skin thanks to its potent dual-action formula, which targets the root causes of breakouts without causing extreme irritation. What makes this gel unique is the balance of its active ingredients; they regulate internal cell turnover to prevent clogged pores and completely eliminate impurities, all while protecting the skin barrier. When applied at night, the lightweight texture absorbs instantly without leaving a greasy residue; although slight flaking is normal during the first few weeks as the skin adjusts, the process is very manageable when using the gentle cleanser and moisturizing lotion included in the Cetaphil kit. After consistent use, I highly recommend this product to anyone looking to reduce blemishes and achieve a visibly clearer, healthier complexion.

I wouldn't buy this product out on pocket before u try it
[I received this product in exchange for my honest review] The consistency is good. I don't really think it's made for all skin types in my opinion I started to used it and not gonna lie I broke out more than I used to.it has no smell

Absolutely would recommend!
[I received this product in exchange for my honest review] While this didn't fully clear up my acne, it helped SO MUCH! Beforehand I did my research, so going in I knew to moisturize a lot! For the first couple weeks I only did it every other day, and moisturized right before and after using it. This gave my skin plenty of time to get to used to it, and I didn't have problems with super red or dry skin at all! (and I have very sensitive skin!) It makes my skin feel so free and clear, and it feels just like putting lotion on. Absolutely worth it and would recommend!




Great acne gel with fast results!
Verified Reviewer
Submitted as part of a sweepstakes entry
Reviewed at

I've been testing the Differin Epiduo Acne Gel for the past few weeks and I've really noticed a great difference in my skin texture. It helped clear up stubborn breakouts without overly drying out my skin. It feels gentle yet effective. This is definitely becoming a staple in my daily skincare routine!
RIP to my skin barrier
Verified Reviewer
Reviewed at

I followed all instructions. I used a pea-sized amount, started out using every other day, and moisturized and ended up with a burning, itching rash all over my face. I ended up needing both oral and topical steroids. Be careful if you have sensitive and stop if you have any burning or redness!