Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
or
Offers
Use previous and next buttons to navigate the slides of the %1 Product Carousel
Earn points on this purchase.
Highlights
Summary
Differin Adapalene 0.1% Acne Treatment Gel is the first and only FDA-approved full prescription strength retinoid. This acne treatment is now available without a prescription. Dermatologist developed and tested.
Benefits
- Clears acne with the power of Rx
- Prevents breakouts, blackheads, whiteheads, blemishes and clogged pores
- Restores skin tone and texture by clearing acne
- Prescription no longer required
- Up to 30-day supply
- Differin Gel can be used to effectively treat acne and "maskne" caused by wearing face masks or facial coverings
Key Ingredients
- Adapalene 0.1%
Item 2509584
Adults and children 12 years of age and older: Use once daily. Clean the skin gently and pat dry before applying the product. Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. Do not use more than one time a day.
Precautions: Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor. If pregnant or breast feeding, ask a doctor before use. Do not use Differin Gel if you are allergic to adapalene or any of the ingredients in the product.
Active: Adapalene 0.1% (retinoid). Inactive: Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified Water, Sodium Hydroxide.
May contain hydrochloric acid to adjust pH.
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Hero Cosmetics
Mighty Patch Original Acne Pimple Patches
Clinique
Clinique Smart Clinical Repair Wrinkle Correcting Serum
La Roche-Posay
Hyalu B5 Pure Hyaluronic Acid Face Serum
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
OLEHENRIKSEN
Pout Preserve Hydrating Peptide Lip Treatment
IT Cosmetics
Do It All Hydrating Sheer Tinted Moisturizer Balm
La Roche-Posay
Toleriane Purifying Foaming Face Wash for Oily Skin
Clinique
Even Better Makeup Broad Spectrum SPF 15 Foundation with Vitamin C
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Eucerin
Radiant Tone Dual Serum Dark Spot Corrector
AmLactin
Intensive Healing Cream with 15% Lactic Acid AHA
Eucerin
Radiant Tone Daily Face Lotion SPF 30 Dark Spot Corrector
Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Best For
Describe Yourself
Skin Type
Most Helpful Positive Review
Thank you Differin!!
I always had clear skin up until I turned 32. I didn't really know how to treat it since I had never had acne before. I tried EVERYTHING- AHA's, BHA's, Retin-A, etc. Retin-A was just way too strong. I never could build up a tolerance. I was always red and DRY- which in turn- made my face worse. I h...
Most Helpful Critical Review
Reduces Acne
I was expecting my acne to be completely gone after using this for weeks. Unfortunately, even though I continuously used this product like instructed, it didn't make as huge of a difference as I expected it to. Don't get me wrong, it does reduce acne, but don't expect all of your acne to be gone.
3155 results
Reliable Solution for Clearer Skin
Verified Reviewer
Reviewed at
Differin has become a key part of my skincare routine. It's gentle but effective, and over time I noticed fewer breakouts and smoother skin. The gel texture is easy to apply and doesn't feel heavy or greasy. At first it took a little patience, but once my skin adjusted, it looked calmer and clearer. I like that it feels reliable for long-term improvement without making my skin too dry. Overall, it's a great product if you want clearer skin and consistent results.
It works!
I am in my late 40s but still deal with acne and skin congestion. This also is supposed to help with aging issues as it is, apparently, a mild retinoid. I had never given this product a real chance but added it in to my routine a couple weeks ago and I am already seeing progress. I am also on an oral antibiotic but have been for a long time. I use the niacinamide serum from Ordinary and salicylic acid face wash, so this all combines to be pretty effective.
Learn to use it!
This product can be SO good if used correctly, it does take time to see progress (took me about 2 months and counting) to see some actual progress but be prepared for the skin dryness/shedding. Moisturize before and after (i use cicaplast) and it helps a lot. I started off once a week for about 3 weeks before doing twice a week. I haven't gotten any crazy breakouts but maybe 1-2 sometimes. Trial and error with this product but it works so good after some time.
Good
Verified Reviewer
Reviewed at
It fights acne well, dries well, and requires the application of a moisturizing cream. The skin is beautiful, soft, shiny, and radiant. The best remedy for problem skin.
Try it
Verified Reviewer
Reviewed at
Ive tried alot of things for my cystic acne and this is the one. It has the texture of an ointment but without the oiliness. It will dry out the area though, so be sure you moisturize.