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Summary
Powered by five bio-engineered peptides inspired by skin’s natural renewal processes, this biotech formula helps enhance the look of firmness, smooth texture, and promote a more youthful-looking complexion. Clinically shown to visibly improve signs of aging in 8 weeks.
Benefits
- Visibly firms and lifts sagging skin
- Rejuvenates the look of skin with vegan anti-wrinkle growth factors
- Restores the look of elasticity
- For all skin types
Key Ingredients
- 5X Vegan Bio-Growth Factor Complex: Mimics skin’s most powerful regenerative signals
- Palmitoyl Tripeptide-5: Visibly firms and reduces the look of deep wrinkles
- CeraPep® Technology: A blend of restorative peptides and ceramides
- Hyaluronic Acid Complex: Brightens and reduces the look of redness
Research Results
- In head-to-head clinical testing, it outperformed the leading growth factor serum in 73% of performance indicators.
- 90% of participants showed overall visible improvement by Week 12 vs. 60% for the leading growth factor serum*
- 100% say skin felt smoother by week 8*
- 100% say their skin appeared more youthful by week 12*
- 100% found the formula gentle and non-irritating*
- 90% noticed skin felt firmer*
- 90% saw improved skin clarity and tone*
- 90% say this product improved their overall skin appearance*
- Clinically proven to firm and lift by week 8*
- Clinically shown to visibly reduce wrinkles in 7 days**
- *Based on a 12-week double-blind IRB-approved clinical trial of 20 participants
- **Based on a clinical study of 17 people after 7 days using a formula containing a key ingredient in this product.
Item 2649265
Apply 1--2 pumps to clean skin in the morning or evening. Can be applied after Needle-less Serum, and before your moisutrizers.
Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum.
This brand is excluded from most Ulta Beauty coupons.
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Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
The glow and firmness I was looking for
I've been using the Needle-less® Growth Factor Serum from DRMTLGY for a few weeks now, and it has honestly become one of my favorite skincare products. The texture is silky and lightweight — it glides on effortlessly, absorbs quickly, and leaves no sticky residue. From the first few days, my skin st...
Most Helpful Critical Review
Not worth the hype
I truly wanted to love this after the reviews. I have mature early 50s skin. I cannot justify paying this much for a product that I use twice a day and does NOT last long. It is much more expensive than a few other brands that deliver the same or better results. Causing me ti go back to what is more...
324 results
Loving so far!
Verified Buyer
Reviewed at

This feels great on my skin. I use at night. My skin feels soft and nourished and looks healthier after a few weeks. Looking to continued results.
Skeptical at first but wrong!
Verified Buyer
Reviewed at

I am halfway through my first bottle of Needle-less and I have to say, I see a difference in the intensity of my forehead lines! I bought this product on a recommendation but wasn't honestly expecting any noticeable results, as been the case with most other products. But I'm pleased to say this one from Drmtlgy is different in a really good way! The price point is also right, which is a huge plus in the facial care/serum space. I will be keeping this product in my face care regimen for sure.
Needle-less growth factor serum
Verified Buyer
Reviewed at

Phenomenal.. best I've ever bought!! You must try this!!
Love The Efficacy RESULTS
Verified Buyer
Reviewed at

I've been using the product for one month and love it. This lightweight, fragrance-free serum definitely has shown to be effective. I see improved elasticity and firmness. I especially notice significant firming at the jowls, jawline and under the neck. It is non-drying, absorbs quickly and I truly appreciate the fragrance-free formulation. My skin really feels smoother and looks firmer only four weeks. Already purchased a second bottle.
Amazing serum
Reviewed at

I absolutely love the Needles Growth Factor Serum. At first, I was a bit concerned because I have very sensitive skin and suffer from rosacea but the serum is actually very gentle and didn't cause any redness. I've been using it for about a month and I can already seen how much my skin has improved! And I'm not the only one! My daughter, who lives in Italy and hadn't seen in person since May, was very impressed with my skin. She asked if I had changed something in my routine because my skin looks firmer than before! At 59 my biggest issues is the loss of firmness especially in my chin area. This serum is really making a difference. I use it along with the needless serum and the results are real! Couldn't be happier!