Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
or
Earn points on this purchase.
Highlights
Summary
Differin Adapalene 0.1% Acne Treatment Gel is the first and only FDA-approved full prescription strength retinoid. This acne treatment is now available without a prescription. Dermatologist developed and tested.
Benefits
- Clears acne with the power of Rx
- Prevents breakouts, blackheads, whiteheads, blemishes and clogged pores
- Restores skin tone and texture by clearing acne
- Prescription no longer required
- Up to 30-day supply
- Differin Gel can be used to effectively treat acne and "maskne" caused by wearing face masks or facial coverings
Key Ingredients
- Adapalene 0.1%
Item 2509584
Adults and children 12 years of age and older: Use once daily. Clean the skin gently and pat dry before applying the product. Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. Do not use more than one time a day.
Precautions: Applying more than directed will not provide faster or better results, but may worsen skin irritation. Children under 12 years of age: ask a doctor. If pregnant or breast feeding, ask a doctor before use. Do not use Differin Gel if you are allergic to adapalene or any of the ingredients in the product.
Active: Adapalene 0.1% (retinoid). Inactive: Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified Water, Sodium Hydroxide.
May contain hydrochloric acid to adjust pH.
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Hero Cosmetics
Mighty Patch Original Acne Pimple Patches
Clinique
Clinique Smart Clinical Repair Wrinkle Correcting Serum
La Roche-Posay
Hyalu B5 Pure Hyaluronic Acid Face Serum
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
ANUA
Azelaic Acid 10 Hyaluron Redness Soothing Serum
BOBBI BROWN
Vitamin Enriched Face Base+ Moisturizer & Primer with Vitamin C + Hyaluronic Acid
The Ordinary
Glycolic Acid 7% Exfoliating and Brightening Daily Toner
TATCHA
The Dewy Skin Cream Line-Plumping Moisturizer
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Clinique
Clinique Smart Clinical Repair Wrinkle Correcting Serum
Clinique
All About Eyes Rich Eye Cream with Hyaluronic Acid
L'Oréal Paris
Revitalift Triple Power Age-Defying Serum
FAQs
How long does it take to see results when using Differin Gel?
Differin Gel is formulated with Adapalene Retinoid, which works deep into pores in 5 minutes. When consistently applied to the full face, you may start to see results in as little as 1 week with best results after 12 weeks.
Can I use Differin Gel if I have sensitive skin?
Differin Gel includes Adapalene an ingredient shown to have improved tolerability resulting in less redness and skin irritation. Apply once daily to dry skin after cleansing. Stop use and consult a dermatologist if irritation becomes severe.
How often should I apply Differin Gel each day?
Use once daily (AM or PM). Clean skin gently and pat dry before applying. Cover the entire face with a thin layer. Do not use more than once a day. Applying more than directed will not provide faster or better results and may worsen skin irritation.
Can I use moisturizer with Differin Gel?
Moisturizing is essential in supporting the skin barrier when using Differin Gel and can help to combat excessive dryness or irritation. Apply Differin Gel to clean, dry skin then follow with non-comedogenic moisturizer and SPF in the AM.
Does Differin Gel cause purging or make acne worse before it gets better?
Acne may appear to worsen within the first few weeks of use as Differin Gel accelerates skin cell turnover. Continue treatment as directed; symptoms should subside between weeks 2-4. If severe irritation occurs stop use and consult dermatologist.
Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Best For
Describe Yourself
Skin Type
Most Helpful Positive Review
Thank you Differin!!
I always had clear skin up until I turned 32. I didn't really know how to treat it since I had never had acne before. I tried EVERYTHING- AHA's, BHA's, Retin-A, etc. Retin-A was just way too strong. I never could build up a tolerance. I was always red and DRY- which in turn- made my face worse. I h...
Most Helpful Critical Review
Reduces Acne
I was expecting my acne to be completely gone after using this for weeks. Unfortunately, even though I continuously used this product like instructed, it didn't make as huge of a difference as I expected it to. Don't get me wrong, it does reduce acne, but don't expect all of your acne to be gone.
3157 results
Please take your time
Trust the process, I would definitely recommend a good moisturizer. Please be careful.
decreased breakouts and smaller pores
Verified Reviewer
Reviewed at
This product has worked wonders for my skin. It decreased the amount of breakouts I have gotten and has made my pores look smaller. I also find that when I do get acne it goes away a lot quicker. When I started using it my skin was peeling very badly, but that's all part of the process, and after a couple of weeks the peeling stops. To decrease irritation and skin peeling, be sure to use the sandwich method — moisturizer then differin then moisturizer again.
great for managing hormonal acne
[I received this product in exchange for my honest review] this give my makeup a beautiful dewy finish without making my skin look too oily. I love how it helps my makeup stay in place while adding a natural glow to my skin. It feels lightweight and leave my makeup looking fresh through the day
Surprising side effect
I'm trying to get rid of closed comedones on one cheek. I've only been on it for about three weeks, but I noticed on the nights I used it (pea-sized amount) I would get a very congested nose that mu usually effective decongestants didn't help. I looked up the side effects and 1-10% of users get rhinitis, sinusitis. So now I only use the tiniest amount and only a few times a week. It seems workable like this. Just a heads-up for other sinus sensitive people.
This is a great product that I continue to purchase over an.
I've been using this product since it became available. For sure recommend.