Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
In stock and ready to ship
Usually ships out in 1-2 days
Earn points on this purchase.
Summary
Highlights
- HSA/FSA eligible
Conscious Beauty at Ulta Beauty™
- Cruelty Free
Murad's Biome-Balancing Clear & Prevent Acne Treatment Serum starts to clear acne in just 3 days, helps prevent breakouts & empowers your biome to thrive for healthier-looking skin.
Benefits
- Clinically proven to help clear active breakouts starting in just 3 days
- Biome-Sensing Tech encourages a healthier, more balanced microbiome that's naturally more resistant to future breakouts
- Clears all types of acne, including whiteheads, blackheads, and hormonal breakouts
- Non-comedogenic, non-drying, non-irritating, layers well under makeup, no pilling or flaking, gentle enough for daily use
Key Ingredients
- Mandelic Acid: an alpha-hydroxy acid (AHA) used to smooth and even the complexion
- Biome-Sensing Tech: encourages a healthier, more balanced microbiome that's naturally more resistant to future breakouts
- Medicated Salicylic Acid: clears and prevents acne, and penetrates deep to decongest clogged pores
- Glutamic Acid: "feeds" the skin's microbiome so it produces GABA, a protective amino acid for healthier-looking, smoother skin
Research Results
- Clearer skin starts in just 3 days*
- Clinically proven to reduce active breakouts, and improve skin health and clarity*
- 92% agree: no unwanted side effects* including peeling, flaking, redness, and irritation
- *Consumer testing on 26 subjects in a 4-week study
- *Expert grading of photos on 26 subjects in a 4-week study
To Use: AM and PM
Cleanse, tone, then apply 1-2 pumps to face and neck, allowing serum to fully absorb before applying moisturizer or SPF during the day. Deep acne bump or breakout? Alternate by applying Biome-Balancing Clear & Prevent Acne Treatment Serum during the day, and spot-treating with Deep Relief Acne Treatment at night.
For external use only. When using this product, skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
Active: Salicylic Acid 1.0%. Inactive: Water (Aqua), Propanediol, Mandelic Acid, Glycerin, Erythritol, Pentylene Glycol, Sodium Polyacryloyldimethyl Taurate, Dimethicone, Sodium Hydroxide, Saccharide Isomerate, Glutamic Acid, Allantoin, Punica Granatum Pericarp Extract, Nelumbo Nucifera Flower Extract, Nymphaea Caerulea Flower Extract, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena (Eggplant) Fruit Extract, Ocimum Basilicum (Basil) Flower/Leaf Extract, Curcuma Longa (Turmeric) Root Extract, Ocimum Sanctum Leaf Extract, Maltodextrin, Glyceryl Polyacrylate, Polysilicone-11, Butylene Glycol, Decyl Glucoside, Tetrasodium Glutamate Diacetate, Citric Acid, Sodium Citrate, 1,2-Hexanediol, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Chlorphenesin.
This brand is excluded from most Ulta Beauty coupons.
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Questions
Ask a QuestionWhat do you want to know about this product?
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
great serum
[I received this product in exchange for my honest review] I recently tried the Murad Blemish Clearing Biome Balancing Treatment Serum and was pleasantly surprised by how effective it is. The texture is lightweight and absorbs quickly into the skin without leaving any residue or stickiness. I love t...
Most Helpful Critical Review
Just ok
[I received this product in exchange for my honest review] I had the opportunity to try out Murad's Biome-Balancing Clear & Prevent Acne Treatment Serum. I honestly wasn't too impressed with this product. I experience acne from time to time, mostly hormonal acne. I typically don't have much luck w...
103 results
Acne Control Serum
The new Murad Acne Control Serum has been prepping my skin for a blemish-free summer. 💙 My hormonal breakouts do not stand a chance with the Salicylic, Glutamic, and Mandelic Acid trio. This Biome-Balancing serum is lightweight and fragrance free making it perfect for am and pm. With the way this works alone I can only imagine the full set. I will define purchasing them all!

Just ok
[I received this product in exchange for my honest review] I had the opportunity to try out Murad's Biome-Balancing Clear & Prevent Acne Treatment Serum. I honestly wasn't too impressed with this product. I experience acne from time to time, mostly hormonal acne. I typically don't have much luck with acne products but was curious about this one. Prior to testing out this product, I was experiencing a fair amount of hormonal acne. I tested this product consistently for 2.5 weeks both am and pm. The formula is a gel based liquid. It's easily spreads and is dispensed from a pump. The formula contains salicylic acid, mandelic acid, Biome-Sensing Tech, and glutamic acid. All which is supposed to help clear acne, even skin tone, and encourage a healthy microbiome. It is said to visibly have results in as little as three days, for me this wasn't the case. I will say, the formula was gentle and I didn't experience any bad effects from using this product. I didn't notice any positive effects to the acne I was experiencing. I will continue to use this and test it out; however at this time I would not repurchase this product. This easily worked into my routine and I did not experience any pilling with my sunscreen or moisturizers.

Gentle and effective
I have been using this serum for a week now and I am truly impressed! It helped calm down a few breakouts within a few days, and my skin feels much smoother after just 1 week of application. I love that it does not dry out my face or make it peel like other acne products. It is quite gentle on my skin. Plus, It is super lightweight and fits perfectly into my morning and night routines. Overall, great serum for anyone who is struggling with acnes or has acne prone skin.

Less stress, less breakouts!
[I received this product in exchange for my honest review] I'm very impressed by this serum! It's lightweight, it sinks in quickly, and doesn't leave any sticky residue. This treats acne without stripping my skin. My barrier feels calm and balanced, even while keeping breakouts in check. If you struggle with acne but hate the dryness or irritation that often comes with treatment products, this is the one to try!

Nice lightweight acne prevention serum
[I received this product in exchange for my honest review] I find it impressive how lightweight the Murad serum is. Unlike other acne serums I've tried, it doesn't leave a sticky residue. Since incorporating this serum into my routine, I've noticed a decrease in acne on my skin, particularly in the T-zone area. I wish the bottle came in a larger size, as I'm concerned about running out quickly. Fortunately, my sensitive skin hasn't experienced any irritation or dryness. I also appreciate that this product is unscented, as my skin can be reactive to fragrances.
