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Highlights
Summary
ma:nyo Bifida Biome Complex Ampoule fortifies the skin barrier. It visibly plumps and nourishes skin's moisture barrier for lasting hydration.
Features
- Bifida that focuses on skin nourishing, creating a balanced skin barrier and lasting hydration while improving skin tone after constant usage.
- Builds a strong foundation for the skin and protect it to make it healthy and firm
- Experience the power with healthy skin layer and strong moisture barrier to prevent future breakouts.
Key Ingredients
- Bifida Biome - Builds up the skin's barrier and keeps well-balanced skin condition.
- 10 Types of Hyaluronic Acid - Penetrates through the skin and fill in every gap between skin layers for ample hydration.
- 5 Probiotics - Strengthens the skin's barrier and helps the skin restore its original complexion.
Formulated Without
- Fragrance
- Silicon
- Paraben
Item 2626987
- Drip 3-5 drops evenly across the face, avoid the eye contour and contact with eyes.
- Lighly massage the ampoule into the skin in a circular motion.
- Finish by gently patting the skin until the essence is fully absorbed.
Bifida Ferment Lysate, Butylene Glycol, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Glycerin, Niacinamide, 1,2-Hexanediol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Aureobasidium Pullulans Ferment, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Cutibacterium Granulosum Ferment Extract Filtrate(5,000ppm), Asiaticoside, Asiatic Acid, Madecassic Acid, Pentylene Glycol, Squalane, Hydrogenated Lecithin, Copper Tripeptide-1, Tromethamine, Acetyl Hexapeptide-8, Propanediol, Ethylhexylglycerin, Dextrin, Water, Caffeine, Benzyl Glycol, Sodium Phytate, Hydrolyzed Algin, Xanthan Gum, Epigallocatechin Gallate, Carbomer, Physalis Alkekengi Calyx Extract, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Laurate, Theobroma Cacao (Cocoa) Seed Extract, Adenosine.
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Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
Lightweight Hydrating Gift from God
[I received this product in exchange for my honest review] Manyo's Bifida Biome Complex Anpoule is effective, gentle skincare that targets skin barrier issues without overwhelming sensitive skin and has a probiotic-packed formula. This Korean skincare gem, priced around $24 depending on the retailer...
Most Helpful Critical Review
It's a good and well-rounded hydrating and soothing serum
It's a good product especially for the price point and ingredients. I was looking for something soothing and hydrating because I was going to start using more aggressive actives so I wanted to see how this would work on my skin before I used such ingredients, but I noticed that while it did work I w...
481 results
Great Hydrating serum
I picked this up because I read ingredients were compersble to Lancome Genefique which i absolutely love but had run out of. It is lightweight and is great at plumping and making the skin feel more hydrated and smooth. Wrinkles and texture and minimized. Skin just looks and feels healthy and did not irritate my very sensitive skin. While not a full dupe for Lacome it is a great busget option especially if youve thought about lancome but are hesitant to make that splurge. I got it as a temporary fix until black friday deals but will keep it in my routine even after I restock Lancome as a way to stretch it. Lancome is longer lasting so i dont feel the need to use twice a day where as this one I do. Its also slighly thicker in texture so it requires a little more on application for anyone considering a switch.
Loved it!
[I received this product in exchange for my honest review] Really enjoyed using this product.The serum is very smooth and not too oily. It left a wonderful feel on my face after applying it. It helped my face feel hydrated and fresh. I had no irritation or acne after using which was a great plus!
Just okay
[I received this product in exchange for my honest review] The consistency feels nice and it was gentle in my skin but I did not notice much improvement to my skin after continued use. Packaging and bottle were nice
This stuff is great
[I received this product in exchange for my honest review] This ampoule is a game-changer for your skin barrier! It's super lightweight, absorbs in seconds, and gives you deep hydration without feeling greasy. The bifida ferments work wonders for soothing irritation and locking in a healthy, plump glow. Perfect to throw into your morning and night routines!

Soothing
[I received this product in exchange for my honest review] This ampoule is a game-changer for your skin barrier! It's super lightweight, absorbs in seconds, and gives you deep hydration without feeling greasy. The bifida ferments work wonders for soothing irritation and locking in a healthy, plump glow. Perfect to throw into your morning and night routines!

Questions
Q&A
Showing 5 out of 13 Questions
- Q
Is this suitable for the neck too?
- Asked by Kc2
- Official Answer By ma:nyo - Brand EngageDear Customer, thank you for reaching out! Yes, this product is suitable and recommended for use on the neck. It is designed to be gentle and suitable for sensitive skin, focusing on strengthening the skin barrier and providing hydration, so it is safe for the delicate neck area. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is this serum oil-free/noncomedogenic?
- Asked by Noncomedogenic
- Official Answer By ma:nyo - Brand EngageDear Customer, thank you for reaching out! Yes, this product is oil-free/non-comedogenic. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can I use retinol serum and snail mucin face cream with this ampoule? If yes, before or after use this ampoule?
- Asked by Em
- Official Answer By ma:nyo - Brand EngageDear Customer, thank you for reaching out! Yes, you can use retinol serum and snail mucin face cream with the ma:nyo Bifida Biome Complex Ampoule. Generally, the ampoule should be applied before the retinol serum and after the snail mucin. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use this alongside the tir tir toner or should i use one or the other?
- Asked by Hek1996
- Official Answer By ma:nyo - Brand EngageDear Customer, Yes, you can use both. Apply the TIRTIR toner first, then follow with the ma:nyo ampoule. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
What is the order of using this product with my Vitamin C serum abs also my Retinoid cream?
- Asked by DB
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! We recommend using your Vitamin C serum in the morning, followed by the ma:nyo Bifida Biome Complex Ampoule. In the evening, apply the ampoule before your retinoid cream. It helps to hydrate and soothe the skin, making it a great buffer between active ingredients.If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you