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Summary
Highlights
ma:nyo Bifida Biome Complex Ampoule fortifies the skin barrier. It visibly plumps and nourishes skin's moisture barrier for lasting hydration.
Features
- Bifida that focuses on skin nourishing, creating a balanced skin barrier and lasting hydration while improving skin tone after constant usage.
- Builds a strong foundation for the skin and protect it to make it healthy and firm
- Experience the power with healthy skin layer and strong moisture barrier to prevent future breakouts.
Key Ingredients
- Bifida Biome - Builds up the skin's barrier and keeps well-balanced skin condition.
- 10 Types of Hyaluronic Acid - Penetrates through the skin and fill in every gap between skin layers for ample hydration.
- 5 Probiotics - Strengthens the skin's barrier and helps the skin restore its original complexion.
Formulated Without
- Fragrance
- Silicon
- Paraben
Item 2626987
- Drip 3-5 drops evenly across the face, avoid the eye contour and contact with eyes.
- Lighly massage the ampoule into the skin in a circular motion.
- Finish by gently patting the skin until the essence is fully absorbed.
Bifida Ferment Lysate, Butylene Glycol, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Glycerin, Niacinamide, 1,2-Hexanediol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Aureobasidium Pullulans Ferment, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Cutibacterium Granulosum Ferment Extract Filtrate(5,000ppm), Asiaticoside, Asiatic Acid, Madecassic Acid, Pentylene Glycol, Squalane, Hydrogenated Lecithin, Copper Tripeptide-1, Tromethamine, Acetyl Hexapeptide-8, Propanediol, Ethylhexylglycerin, Dextrin, Water, Caffeine, Benzyl Glycol, Sodium Phytate, Hydrolyzed Algin, Xanthan Gum, Epigallocatechin Gallate, Carbomer, Physalis Alkekengi Calyx Extract, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Laurate, Theobroma Cacao (Cocoa) Seed Extract, Adenosine.
Free gift with purchase
Free gift with purchase
Free 3 piece gift with $35 skincare purchase (valid thru 8.2.25 on in store or shipped purchases. Full or partial pickup or same day delivery purchases do not qualify. While quantities last and subject to in store availability)
Free gift with purchase
Free double cleansing set with $20 Ma:nyo purchase (valid thru 7/26/25 on in store or shipped purchases. Full or partial pickup or same day delivery purchases do not qualify. While quantities last and subject to in store availability)
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Questions
Ask a QuestionQ&A
Showing 5 out of 10 Questions
- Q
Can i use this alongside the tir tir toner or should i use one or the other?
- Asked by Hek1996
- Official Answer By ma:nyo - Brand EngageDear Customer, Yes, you can use both. Apply the TIRTIR toner first, then follow with the ma:nyo ampoule. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
What is the order of using this product with my Vitamin C serum abs also my Retinoid cream?
- Asked by DB
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! We recommend using your Vitamin C serum in the morning, followed by the ma:nyo Bifida Biome Complex Ampoule. In the evening, apply the ampoule before your retinoid cream. It helps to hydrate and soothe the skin, making it a great buffer between active ingredients.If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Would I use this product before or after my vit c serum in the morning?
- Asked by DBO
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! In the morning, apply your Vitamin C serum first, then follow with the ma:nyo Bifida Biome Complex Ampoule. This helps lock in hydration and support your skin barrier. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use a vitamin C serum with this ampoule? If so, should the serum or ampoule be applied first? Can i apply one product immediately after the other, or do i need to wait for the PH to balance?
- Asked by Old
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You may use a Vitamin C serum with the ma:nyo Bifida Biome Complex Ampoule. Apply the Vitamin C serum first, followed by the ampoule. There’s no need to wait between steps—both can be applied one after the other. The ampoule helps soothe and hydrate the skin, making it a great pairing with active ingredients like Vitamin C. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Do I need a toner prior to use or can I just use a moisturizer after applying this product to my skin?
- Asked by Rose
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You can use ma:nyo Bifida Biome Complex Ampoule after toner. Using a toner can help prep your skin and boost absorption. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
High quality hydration at a sensible price!
[I received this product in exchange for my honest review] After consistent use, the Manyo Bifida Biome Complex Ampoule has earned a permanent spot in my skincare routine — and here's why. ✨ Texture & Application The ampoule has a lightweight, serum-like texture that absorbs quickly without leaving...
Most Helpful Critical Review
Made my skin itchy and even more dry
[I received this product in exchange for my honest review] I was super excited to try this product as I've heard a lot of great things about it on social media, but I have to be honest. I am highly dissatisfied with this product and the way he performs. A little background on my skin type. I am very...
213 results
Great as part of my skincare routine
[I received this product in exchange for my honest review] This serum is great for hydrating and brightening my skin. It goes on smooth and has no scent. I like that it is easy to apply and I have been using it in the morning and at night as part of my skincare routine.
Loving this K-Beauty Serum
I recieved this product in exchange for my honest review. First off, I love the packaging! Super easy to open, the bottle is glass and dropper is great quality. The serum is fragrance free, which is great for my sensitive skin. I've been using it for a few weeks now, my skin feels more hydrated and looks smoother. It goes on a little tacky, but dries down quickly. I think this is a nice product and I would recommend giving it a try!
I have used this serum for more than two weeks and it works
Love this serum! The packaging feels high-end, and the dropper makes it easy to use. Texture is light and sinks in fast — no stickiness. It calms my skin, adds glow, and makes it feel stronger. No strong scent, just clean. Great ingredients like Bifida and niacinamide really work. Definitely a keeper!
Incredibly good!
[I received this product in exchange for my honest review] This ampoule is like a fragrance-free probiotic smoothie for your face. It goes on like a light serum—not sticky, not greasy, just smooth—and sinks in fast. It feels super calming, especially if your skin's acting irritated or stressed. You probably won't wake up with glowing glass skin overnight, but with regular use, it helps your skin feel stronger, less reactive, and more balanced. Great under other serums or moisturizers, and it plays well with actives. I apply it before a lifting facial oil on recovery nights, and it is amazing. If your skin's ever tired, sensitive, or needs a reset, this is one of those quiet products that does the work without showing off.
Gentle, Hydrating, and Makeup-Friendly
[I received this product in exchange for my honest review] It doesn't have a detectable scent, which I really appreciate. The texture is lightweight and absorbs fast without leaving any sticky or greasy residue. I love that it layers beautifully under makeup without causing any pilling or messing with the finish. Best of all, it doesn't irritate my sensitive skin. It feels gentle and safe to use every day, even when my skin is feeling a little reactive. After using it consistently, my skin feels more hydrated and looks noticeably smoother and plumper. It gives my skin that healthy, well-moisturized look without feeling heavy. A great everyday serum that delivers visible results.
