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Highlights
Summary
DERMA E's Anti-Wrinkle Renewal Cream delivers targeted wrinkle correction with weightless hydration. Derm-recommended Retinol works synergistically with Bakuchiol to refine texture and visibly soften fine lines, while Vitamin E and Panthenol support the skin barrier and boost skin’s resilience.
Benefits
- Helps visibly reduce the look of fine lines and wrinkles
- Nourishes and smooths skin for a healthier-looking complexion
- Soothes and supports skin barrier health
- Provides lightweight, all-day hydration
Key Ingredients
- RETINOL: #1 dermatologist-recommended ingredient to reduce the appearance of fine lines and wrinkles†
- PANTHENOL (PRO-VITAMIN B5): a moisture-binding ingredient that strengthens the skin barrier and improves smoothness
- BAKUCHIOL: a gentle, plant-based retinol alternative that helps smooth texture and reduces the look of lines
- VITAMIN E: a nourishing antioxidant that helps protect skin from dryness and leaves skin soft and supple
- ALLANTOIN: a soothing skin protectant that helps keep skin smooth and calm
- †Based on an internal survey of 35 dermatologists.
Research Results
- 97% saw reduced fine lines and wrinkles †
- † Results based on single use independent clinical study after 8 weeks using the Anti-Wrinkle Collection (Cleanser, Oil, Night Treatment, Smoothing Eye Cream, and Renewal Cream)
Item 2556321
Apply onto clean face and neck. Use in the evening.
Tip: Be sure to apply ample SPF in the morning to keep skin protected!
Purified Water, Carthamus Tinctorius (Safflower) Seed Oil, Stearic Acid (Vegetable Derived), Glycerin (Vegetable Derived), Glyceryl Stearate SE, Cetyl Alcohol (Plant Derived), Microcrystalline Cellulose (Plant Derived), Cellulose Gum (Plant Derived), Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Bakuchiol, Retinol, Panthenol (Provitamin B5), Tocopheryl Acetate (Vitamin E), Allantoin, Phenoxyethanol, Ethylhexylglycerin, Natural Fragrance Oils.
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Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Best For
Describe Yourself
Skin Type
Most Helpful Positive Review
If you have tough skin: 10/10!!!
Im 24, 1/2 Asian, 1/2 white, I have very combination to dry skin, and pretty tolerant skin with Minimal breakouts. So take my review with a grab of salt if you have sensitive or difficult, acne prone skin. I am IN LOVE with this product. I love that it is truly effective on my face. Im pretty inco...
Most Helpful Critical Review
Formula is a little greasy
I found this formula very greasy for my face and started to breakout with acne after using. I don't typically have acne, maybe the occasional pimple at worst. However, I now use it as a hand cream and it feels luxurious when used as a hand cream. I bought this cream as an alternative to R&F Redefine...
271 results
Baby Powder scent has me gagging
This moisturizer is lightweight, and feels amazing on the skin. A little goes a long way! I love it. However, the powdery scent is over the top and doesn't go away! I absolutely cannot stand powder-scents of any kind (think baby powder). So I am returning. It's that bad. If the scent would go away after applying, I could live with it. But I walk around and keep wafting strong baby powder, and it's literally nauseating.
First Night
I stopped by my local Ulta today for foundation and as I passed by an aisle I saw this. I just turned 30 and have noticed fine lines along my forehead. I have not done research on DERMA.E before and bought this as a " spur of the moment " purchase … After one time of application Ive ALREADY seen results!! I'm not someone who usually has ANY type of luck but I had some today! Can't wait to see more results!!
Great product at a great price.
Verified Buyer
When I can't get my normal moisturizer I use this product. I love that it can be used day or night and makes my skin feel soft
I plan on buying this again.
Verified Buyer
Reviewed at
I use this every morning under my makeup. Love it. A little goes a long way.
I have bought this 4 times now
Been using this for a few years. I'm 32, no major skin issues except oilier in the summer and dry in the winter. I wear this to work at the hospital I'm there 13 hours and I don't get oily. Also, I'm a nurse so through the stress and physical activity I don't get oily and makeup stays put. I'll alternate with bb cream or powder foundation it still works great under. I should make a video on this now that I think of it. It just wears well all day. If you're oily, you won't get so oily after applying it and it goes well under makeup is my point. Like I won't look so oily. I wear this at home when I don't go out and at work. I usually go for spf moisturizers on errand days or outings and those already leave me more oily or dewy. I will buy this stuff forever. They used to name it day cream and I keep using it during the day lol but I wear it mostly at work because I'm not exposing my skin to the sun and it leave me skin real pretty and never oily for those 13 hours. I have normal combo skin.
Questions
Q&A
Showing 5 out of 6 Questions
- Q
Does this have any peptides in it?
- Asked by Lisa
- Official Answer By DERMA E - Brand EngageIf you're looking for peptides, we recommend our Advanced Peptides and Flora-Collagen line!Was this answer helpful to you
- Q
Is this used as a moisturizer, or should I still follow it up with my normal daily moisturizer?
- Asked by Cris
- Official Answer By DERMA E - Brand EngageThis is to be used as a moisturizer.Was this answer helpful to you
- Q
What is the retinol percentage?
- Asked by C
- Official Answer By DERMA E - Brand EngageThank you for your interest in our ingredients. While we don't disclose the exact percentage of retinol this formula, I can tell you that it is always formulated at the concentration recommended for maximum results without irritation. Beyond that, it’s good to know that the percentage of an ingredient in a formula is just one part of the story. When designing each formula, DERMA E carefully considers the product’s effectiveness, natural content, pH balance, gentleness and safety.Was this answer helpful to you
- Q
Does this product come in a box?
- Asked by Jam
- Official Answer By DERMA E - Brand EngageThis product is not packaged in a box.Was this answer helpful to you
- Q
I'm a little confused, the picture of the container doesn't have the word retinol in it nor did I see any forms of retinol in the ingredient listing. Why is the title of this product page have the word retinol in it?
- Asked by michelle
- Official Answer By DERMA E - Brand EngageHere are the ingredients, including retinol (the 7th to last ingredient): "Purified Water, Carthamus Tinctorius (Safflower) Seed Oil, Stearic Acid (Vegetable Derived), Glycerin (Vegetable Derived), Glyceryl Stearate SE, Cetyl Alcohol (Plant Derived), Microcrystalline Cellulose (Plant Derived), Cellulose Gum (Plant Derived), Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Helianthus Annuus (Sunflower) Seed Oil, Bakuchiol, Retinol, Panthenol (Provitamin B5), Tocopheryl Acetate (Vitamin E), Allantoin, Phenoxyethanol, Ethylhexylglycerin, Natural Fragrance Oils."Was this answer helpful to you