Apply a thin layer to entire face twice a day after cleansing. If skin feels a little dry, Clinique suggests using a lightweight, oil-free hydrator, like Dramatically Different Moisturizing Gel.
As a spot treatment:
Spot-apply where needed. Using other topical acne drugs at the same time or right after use of this product may increase dryness or irritation of skin. If this occurs, only one medication should be used unless directed by a doctor. If you are currently using Clinique's Acne Solutions Clear Skin System, use Clinical Clearing Gel as a spot treatment only.