Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
Highlights
Summary
Hypothesis Eczema Relief + Repair Duo addresses eczema flare-ups at the source. Microbiome-friendly hydrogel is formulated with patented TPZ-01™ enzyme to target & kill Staph aureus bacteria while restoring skin's natural balance, while the eczema cream locks in moisture & soothes itching.
Benefits
- 2-piece set of eczema essentials targets the bacteria behind eczema flares + deeply hydrates
- Microbiome-friendly Eczema Precision Hydrogel is formulated with precision TPZ-01™enzyme to target eczema-associated Staph aureus bacteria while preserving beneficial microbes
- Deeply nourishing Eczema Therapy Cream for face and body seals in moisture and restores the skin barrier
- 2-step routine relieves the irritation, itching and redness of eczema while balancing the skin’s protective microbiome
- Dermatologist approved, hypoallergenic and clinically tested for safety and efficacy
- Accepted by the National Eczema Association (NEA) and EWG Verified®
- Certified Microbiome-Friendly for Eczema by MyMicrobiome
- Steroid free and fragrance free
- Cruelty free and Leaping Bunny certified
Key Ingredients
- The patented TPZ-01™ enzyme selectively targets and kills 99.99% of eczema-associated Staph aureus bacteria within 5 minutes while preserving beneficial microorganisms
- 1% colloidal oatmeal soothes itching and calms irritation from eczema
- Pro-Vitamin B5 and Sorbitol are two potent moisture magnets that hydrate, comfort, and help replenish the skin barrier
- 3 essential ceramides work in tandem to help restore the skin’s natural moisture barrier
- An advanced moisture complex of hyaluronic acid, sodium PCA, urea, and glycerin provide immediate hydration for dry, irritated skin
- Bisabolol, the key anti-inflammatory component in chamomile, helps to reduce redness
Includes
- Eczema Precision Hydrogel 80 mL
- Eczema Therapy Cream 200 mL
Item 77005805
- Apply Eczema Precision Hydrogel to eczema-prone skin at least twice daily (morning and evening) or as often as desired. Let absorb into the skin for 5 minutes before layering on other skincare.
- Follow with Eczema Therapy Cream as part of a comprehensive eczema regimen.
- Apply Eczema Therapy Cream to body and face as often as needed to lock in moisture, soothe itch, and calm dry, eczema-prone skin.
Eczema Precision Hydrogel Active Ingredient: 0.01% Colloidal Oatmeal, Inactive Ingredients:Water/Aqua/Eau, Sorbitol, Arginine HCl, Hydroxyethylpiperazine Ethane Sulfonic Acid, Panthenol, Sodium Chloride, Hydroxypropyl Methylcellulose, Methionine, Calcium Chloride, Methylparaben, Sodium Hydroxide, Acetyl Cysteine, sr-(Staphylococcus sp. Polypeptide-1 Dipeptide-81 Streptococcus Suis Phage Polypeptide-1 Dipeptide-19 Hexapeptide-40), Hydrochloric Acid
Eczema Therapy Cream Active Ingredient: 1% Colloidal Oatmeal, Inactive Ingredients: Water/Aqua/Eau, Glycerin, Caprylic/Capric Triglyceride, Cetyl Alcohol, Bis-Diglyceryl Polyacyladipate-2, Jojoba Esters, Polyglyceryl-2 Stearate, Butyrospermum Parkii (Shea) Butter, Bisabolol, Zingiber Officinale (Ginger) Extract, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Sodium PCA, Urea, Trehalose, Sodium Hyaluronate, Hexylene Glycol, Polyquaternium-51, Triacetin, Caprylyl Glycol, Sodium Lauroyl Lactylate, Tocopherol, Tocopheryl Acetate, Dimethicone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Hydroxyacetophenone, Glyceryl Stearate, Stearyl Alcohol, Carbomer, Xanthan Gum, 1,2-Hexanediol, Citric Acid, Sodium Hydroxide, Tetrasodium Glutamate Diacetate, Ethylhexylglycerin
This brand is excluded from most Ulta Beauty coupons.
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
98 results
Relief
Since using hypothesis products, the itching and soreness of my eczema, has decreased to the point where it is manageable. I'm very pleased to have discovered the product and am recommending it to anyone and everyone who deals with eczema. Thank you.
Hypothesis is the best eczema solution I've used.
My 6-year-old has struggled with eczema since he was a baby. For a short period, it actually seemed to self improve while he was going through OIT for a peanut allergy. Thankfully he's beaten the allergy, but once he started to eat more peanuts on a regular basis, the eczema flare-ups came back. I heard about Hypothesis through a friend and decided to give it a try. To say the results were incredible is an understatement. Within just a couple of weeks his red, itchy skin completely returned to normal...and for the first time he didn't complain at all about stinging or burning from the spray or serum. I'll always keep this on hand for future flare-ups.
Works So Well I Don't Mind the Smell
I was using consistently when I first got the set, and saw great results. I stopped using it after a week after going throughout my day and getting whiffs of it. The smell is very odd, highly medicinal and naturally funky at the same time. After not using it for a few days, my skin went back to square one. I decided the odd smell was worth my skin relief. Now I put a nice smelling lotion that I know doesn't irritate my skin as the last step-not over the Hypothesis products, but near it-and it masks it enough. If you're not wanting to get the full set, I feel like the gel and cream are the most efficient. In the future I think I will just get these two. I've tried literally a million products and the Hypothesis set genuinely helps calm my sandpaper skin on my neck like nothing else.
Relief and repair
This is the first product in years that I've found has helped my eczema and not made it worse. These are some before and after pictures of just my hands.


Excellent products for eczema!!!
I am very impressed with these products. Truthfully, I didn't expect them to work as well as they do. But I wanted to give them a chance. I ordered the complete eczema care set and have used the products as directed now for about two weeks. I can honestly say my skin has shown major reductions in itching and redness. I couldn't be happier with results I have obtained from using these products.