Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
Offers
Use previous and next buttons to navigate the slides of the %1 Product Carousel
Yay! You're earning points!
Highlights
Summary
Phyto Nature E² is an advanced daily leave-on with exosomes + enzymes that accelerates skin renewal. Pumpkin Enzyme exfoliates for smoother, brighter skin. Turmeric stem cells + Acacia reduce lines; botanicals deliver exfoliation, hydration, and antioxidant protection.
Benefits
- Accelerates skin’s natural cellular renewal
- Resurfaces to reveal brighter, smoother skin every day
Key Ingredients
- Regenerative Exosome Blend: acts in multiple layers of skin's surface, visibly diminishing fine lines + wrinkles
- Pumpkin Enzyme: exfoliates to reveal brighter, smoother skin daily
- Botanical Blend with Phyto Glycogen + Prickly Pear: visibly brightens + smooths
- Bio-fermented Acetyl Glucosamine: hydrates + provides antioxidant protection
Research Results
- Improves natural regeneration by 86%*
- Visibly diminishes fine lines + wrinkles in 2 weeks**
- 1 use skin looks + acts younger***
- *Versus untreated skin. Based on in vitro testing.
- **Results at 2 weeks, based on a reduction in visible signs of skin aging in an independent clinical study with 32 subjects, 2 applications/day
- ***Consumer perception results after 1 use. Based on an 8 week independent clinical study with 32 subjects, 2 applications/day.
Item 2647233
Apply to clean skin. Allow to absorb, then follow with the rest of your skin care routine. Use twice daily.
Keep out of reach of children.
Water/Aqua/Eau, Lactobacillus/Pumpkin Ferment Extract, Propanediol, Lactococcus Ferment Lysate, Ethoxydiglycol, Hydrolyzed Soy Protein, Acetyl Glucosamine, Hydroxyacetophenone, Lactic Acid, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Citrus Limon (Lemon) Peel Oil, Citrus Aurantium Dulcis (Orange) Peel Oil, Salvia Sclarea (Clary) Oil, Pyrus Malus (Apple) Fruit Extract, Viola Odorata Leaf Extract, Acacia Senegal Gum Extract, Curcuma Longa (Turmeric) Root Extract, Mucor Miehei Extract, Lavandula Spica (Lavender) Flower/Leaf/Stem Extract, Rosmarinus Officinalis (Rosemary) Leaf Oil, Litsea Cubeba Fruit Oil, Camellia Japonica Flower Extract, Glycerin, Mentha Piperita (Peppermint) Oil, Butylene Glycol, Lactobacillus Ferment, Glycogen, Urea, Caprylyl Glycol, Phospholipids, Glucosamine HCl, Xanthan Gum, PEG-40 Hydrogenated Castor Oil, 1,2-Hexanediol, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Citric Acid, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Sodium Chloride, Sodium Citrate, Disodium EDTA, Sodium Benzoate, Potassium Sorbate, Limonene, Linalool, Citral.
This brand is excluded from most Ulta Beauty coupons.
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Questions
Ask a QuestionWhat do you want to know about this product?
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
128 results
This product works!
gifted by dermalogica complimentary of dermalogica I've been using the Phyto Nature E² Regenerating Daily Exosome Leave-On Treatment twice a day since late November, and I can honestly say this product delivers. I was hesitant about the price at first, but the results make it completely worth it. I'm in my mid-thirties with combination skin, and this treatment has become one of the few products I can genuinely recommend without hesitation. Within a couple of weeks, I noticed a visible softening of fine lines and an overall smoother, brighter look to my skin. The exfoliating enzymes gently clear away dull surface cells, while the exosome blend works deeper to support firmness and renewal. My skin looks more refreshed, more even, and noticeably more resilient day to day. If you're dealing with mature or prematurely aging skin, fine lines, wrinkles, or a loss of firmness, this is absolutely worth considering. It's lightweight, silky, and truly feels like it reawakens your skin's natural renewal process. I love this product and plan to keep it in my routine long-term.

Great
Loving this serum gifted by dermalogica. It's unlike anything I've used before. It makes my skin feel smooth and rejuvenated. It's hydrating on my skin
The future of skincare!
I have to say that this has shown me great results despite the few uses I've had. I can see why people keep saying that exosomes are the future of skincare! One use of this and my skin was visibly more glowy and even. My scars also appeared smaller and by the end of the week my fine lines also were reduced. I received this complimentary of dermalogica one week after microneedling so it came to me at such a great time. Love my results! #gifted by dermalogica
Great addition to my daily skincare routine!
This gel-like texture absorbs effortlessly into my skin and leaves no greasy or sticky residue. The natural, herbal scent gives me a calming and relaxing feeling while applying it and even minutes after. I have dry skin, and this has been a great help in making my skin look more nourished. It has been a wonderful addition to my daily routine, and after a few weeks, I can see an improved overall appearance in my skin. I've noticed even better results after using it for several months. My fine lines seem diminished, and my skin tone looks brighter and more even. This is a beautiful product, and I'm so glad I've been able to use it. Gifted by dermalogica

love it
Gifted my Demalogica. I have been using this serum for 2 weeks now and I love it. It has really helped with the wrinkles on my forhead. I wanted a serum that would make my wrinkles less noticeble. Love it!