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Highlights
Summary
Powered by five bio-engineered peptides inspired by skin’s natural renewal processes, this biotech formula helps enhance the look of firmness, smooth texture, and promote a more youthful-looking complexion. Clinically shown to visibly improve signs of aging in 8 weeks.
Benefits
- Visibly firms and lifts sagging skin
- Rejuvenates the look of skin with vegan anti-wrinkle growth factors
- Restores the look of elasticity
- For all skin types
Key Ingredients
- 5X Vegan Bio-Growth Factor Complex: Mimics skin’s most powerful regenerative signals
- Palmitoyl Tripeptide-5: Visibly firms and reduces the look of deep wrinkles
- CeraPep® Technology: A blend of restorative peptides and ceramides
- Hyaluronic Acid Complex: Brightens and reduces the look of redness
Research Results
- In head-to-head clinical testing, it outperformed the leading growth factor serum in 73% of performance indicators.
- 90% of participants showed overall visible improvement by Week 12 vs. 60% for the leading growth factor serum*
- 100% say skin felt smoother by week 8*
- 100% say their skin appeared more youthful by week 12*
- 100% found the formula gentle and non-irritating*
- 90% noticed skin felt firmer*
- 90% saw improved skin clarity and tone*
- 90% say this product improved their overall skin appearance*
- Clinically proven to firm and lift by week 8*
- Clinically shown to visibly reduce wrinkles in 7 days**
- *Based on a 12-week double-blind IRB-approved clinical trial of 20 participants
- **Based on a clinical study of 17 people after 7 days using a formula containing a key ingredient in this product.
Item 2649265
Apply 1--2 pumps to clean skin in the morning or evening. Can be applied after Needle-less Serum, and before your moisutrizers.
Water/Aqua/Eau, Glycerin, Butylene Glycol, Pentylene Glycol, Maltodextrin, Coco-Caprylate/Caprate, Saccharide Isomerate, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Ceramide NP, Folic Acid, Phytosphingosine, Ceramide AP, Ceramide EOP, Triheptanoin, Chiretta (Swertia Chirata) Extract, Phenoxyethanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C9-12 Alkane, Polyurethane-100, Ethylhexylglycerin, Sodium Hydroxide, Lecithin, Trisodium Ethylenediamine Disuccinate, Acetyl Glutamine, 1,2-Hexanediol, Mushroom (Tremella Fuciformis) Sporocarp Extract, Hydrolyzed Hyaluronic Acid, Decyl Glucoside, Bacillus/Soybean Ferment Extract, Sodium Lauroyl Lactylate, Caprylyl Glycol, Carbomer, Polysorbate 20, Cholesterol, Xanthan Gum.
This brand is excluded from most Ulta Beauty coupons.
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Reviews
Review Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
The glow and firmness I was looking for
I've been using the Needle-less® Growth Factor Serum from DRMTLGY for a few weeks now, and it has honestly become one of my favorite skincare products. The texture is silky and lightweight — it glides on effortlessly, absorbs quickly, and leaves no sticky residue. From the first few days, my skin st...
Most Helpful Critical Review
Not worth the hype
I truly wanted to love this after the reviews. I have mature early 50s skin. I cannot justify paying this much for a product that I use twice a day and does NOT last long. It is much more expensive than a few other brands that deliver the same or better results. Causing me ti go back to what is more...
335 results
Amazing results
Verified Buyer
Reviewed at

This serum packs a punch. I have extremely sensitive skin, that is reddish pink. I have used this for a few months with zero irritation. The texture of my skin has changed and I am beyond thrilled with my results.
Needless Growth Factor Serum
Verified Buyer
Reviewed at

I am on my second bottle of this and can't say enough good things about it. The science behind it is why I ordered. I have tried the TNS Growth Factor from Skin Medica and I will say I believe this serum has given me better results at a fraction of the cost for the TNS. My wrinkles have significantly decreased and my skin overall just appears firmer. Will continue to purchase. It is a little pricey but considering all the benefits I believe its worth the price!
Great!
Verified Buyer
Reviewed at

I love all DRMTLGY products and this is no exception. Every time I try a new brand, I always come back to this one! They are clean, no fragrance go on beautifully and Iove them all! I'm 60 and my skin looks really good. I combine this with peptide cream in the day. I use growth serum at night.
Just Starting
Verified Buyer
Reviewed at

I just started using the Needle-less Growth Factor Serum. I was surprised how lightweight it was. It doesn't feel heavy or tacky on my face. If it performs like my other DRMTLGY products, Tinted Moisturizer with SPF, Pumpkin Enzyme Maske, Brightening Eye Masks, and the all-timt GOAT, Luminous Eye Corrector with SPF I know I won't be disappointed.
OBSESSED!!
Verified Buyer
Reviewed at

Don't hesitate! Buy it!!! Within a week of using it twice a day people were complimenting my skin and asking what I was doing differently.