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Highlights
Summary
ma:nyo Bifida Biome Complex Ampoule fortifies the skin barrier. It visibly plumps and nourishes skin's moisture barrier for lasting hydration.
Features
- Bifida that focuses on skin nourishing, creating a balanced skin barrier and lasting hydration while improving skin tone after constant usage.
- Builds a strong foundation for the skin and protect it to make it healthy and firm
- Experience the power with healthy skin layer and strong moisture barrier to prevent future breakouts.
Key Ingredients
- Bifida Biome - Builds up the skin's barrier and keeps well-balanced skin condition.
- 10 Types of Hyaluronic Acid - Penetrates through the skin and fill in every gap between skin layers for ample hydration.
- 5 Probiotics - Strengthens the skin's barrier and helps the skin restore its original complexion.
Formulated Without
- Fragrance
- Silicon
- Paraben
Item 2626987
- Drip 3-5 drops evenly across the face, avoid the eye contour and contact with eyes.
- Lighly massage the ampoule into the skin in a circular motion.
- Finish by gently patting the skin until the essence is fully absorbed.
Bifida Ferment Lysate, Butylene Glycol, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Glycerin, Niacinamide, 1,2-Hexanediol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Aureobasidium Pullulans Ferment, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Cutibacterium Granulosum Ferment Extract Filtrate(5,000ppm), Asiaticoside, Asiatic Acid, Madecassic Acid, Pentylene Glycol, Squalane, Hydrogenated Lecithin, Copper Tripeptide-1, Tromethamine, Acetyl Hexapeptide-8, Propanediol, Ethylhexylglycerin, Dextrin, Water, Caffeine, Benzyl Glycol, Sodium Phytate, Hydrolyzed Algin, Xanthan Gum, Epigallocatechin Gallate, Carbomer, Physalis Alkekengi Calyx Extract, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Laurate, Theobroma Cacao (Cocoa) Seed Extract, Adenosine.
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Questions
Ask a QuestionQ&A
Showing 17 out of 12 Questions
- Q
Is this serum oil-free/noncomedogenic?
- Asked by Noncomedogenic
- Official Answer By ma:nyo - Brand EngageDear Customer, thank you for reaching out! Yes, this product is oil-free/non-comedogenic. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can I use retinol serum and snail mucin face cream with this ampoule? If yes, before or after use this ampoule?
- Asked by Em
- Official Answer By ma:nyo - Brand EngageDear Customer, thank you for reaching out! Yes, you can use retinol serum and snail mucin face cream with the ma:nyo Bifida Biome Complex Ampoule. Generally, the ampoule should be applied before the retinol serum and after the snail mucin. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use this alongside the tir tir toner or should i use one or the other?
- Asked by Hek1996
- Official Answer By ma:nyo - Brand EngageDear Customer, Yes, you can use both. Apply the TIRTIR toner first, then follow with the ma:nyo ampoule. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
What is the order of using this product with my Vitamin C serum abs also my Retinoid cream?
- Asked by DB
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! We recommend using your Vitamin C serum in the morning, followed by the ma:nyo Bifida Biome Complex Ampoule. In the evening, apply the ampoule before your retinoid cream. It helps to hydrate and soothe the skin, making it a great buffer between active ingredients.If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Would I use this product before or after my vit c serum in the morning?
- Asked by DBO
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! In the morning, apply your Vitamin C serum first, then follow with the ma:nyo Bifida Biome Complex Ampoule. This helps lock in hydration and support your skin barrier. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use a vitamin C serum with this ampoule? If so, should the serum or ampoule be applied first? Can i apply one product immediately after the other, or do i need to wait for the PH to balance?
- Asked by Old
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You may use a Vitamin C serum with the ma:nyo Bifida Biome Complex Ampoule. Apply the Vitamin C serum first, followed by the ampoule. There’s no need to wait between steps—both can be applied one after the other. The ampoule helps soothe and hydrate the skin, making it a great pairing with active ingredients like Vitamin C. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Do I need a toner prior to use or can I just use a moisturizer after applying this product to my skin?
- Asked by Rose
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You can use ma:nyo Bifida Biome Complex Ampoule after toner. Using a toner can help prep your skin and boost absorption. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is it safe to use in AM? It does have lactic acid in it
- Asked by N
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! Yes, you can safely use ma:nyo Bifida Biome Complex Ampoule in the morning. It’s gentle enough for daily use. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can this ampule be used with the SolaWave tools- 4n1 Wand?
- Asked by Skincare Junkie
- Official Answer By ma:nyo - Brand EngageDear Customer, our ma:nyo Bifida Biome Complex Ampoule is generally safe to use with beauty devices. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is this a good product for a open pores and oily skin?
- Asked by krishi
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! Yes our ma:nyo Bifida Biome Complex Ampoule is a great product for improving skin texture, strengthening the skin barrier, soothing sensitive skin, and providing deep hydration. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use a vitamin C serum with this ampoule? If so, should the serum or ampoule be applied first? Can i apply one product immediately after the other, or do i need to wait for the PH to balance?
- Asked by Old
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You may use a Vitamin C serum with the ma:nyo Bifida Biome Complex Ampoule. Apply the Vitamin C serum first, followed by the ampoule. There’s no need to wait between steps—both can be applied one after the other. The ampoule helps soothe and hydrate the skin, making it a great pairing with active ingredients like Vitamin C. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Do I need a toner prior to use or can I just use a moisturizer after applying this product to my skin?
- Asked by Rose
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You can use ma:nyo Bifida Biome Complex Ampoule after toner. Using a toner can help prep your skin and boost absorption. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is it safe to use in AM? It does have lactic acid in it
- Asked by N
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! Yes, you can safely use ma:nyo Bifida Biome Complex Ampoule in the morning. It’s gentle enough for daily use. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can this ampule be used with the SolaWave tools- 4n1 Wand?
- Asked by Skincare Junkie
- Official Answer By ma:nyo - Brand EngageDear Customer, our ma:nyo Bifida Biome Complex Ampoule is generally safe to use with beauty devices. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is this a good product for a open pores and oily skin?
- Asked by krishi
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! Yes our ma:nyo Bifida Biome Complex Ampoule is a great product for improving skin texture, strengthening the skin barrier, soothing sensitive skin, and providing deep hydration. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Is this a good product for someone with oily skin?
- Asked by mya
- Official Answer By ma:nyo - Brand EngageDear Customer, Yes, the ma:nyo Bifida Biome Complex Ampoule is suitable for oily skin. Its lightweight, watery texture absorbs quickly without leaving a greasy residue, making it ideal for layering in multi-step routines. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can I use this before/after with retinol?
- Asked by Cat
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You can use ma:nyo Bifida Biome Complex Ampoule with retinol to strengthen the skin barrier. However, since everyone's skin reacts differently, it's best to patch test first before regular use. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
Lightweight Hydrating Gift from God
[I received this product in exchange for my honest review] Manyo's Bifida Biome Complex Anpoule is effective, gentle skincare that targets skin barrier issues without overwhelming sensitive skin and has a probiotic-packed formula. This Korean skincare gem, priced around $24 depending on the retailer...
Most Helpful Critical Review
It's a good and well-rounded hydrating and soothing serum
It's a good product especially for the price point and ingredients. I was looking for something soothing and hydrating because I was going to start using more aggressive actives so I wanted to see how this would work on my skin before I used such ingredients, but I noticed that while it did work I w...
460 results
Plumping
[I received this product in exchange for my honest review] Nice hydrating serum, seems to plump skin and does not feel heavy on the skin. Does leave skin a bit tacky but absorbs quickly. Nice to layer under other moisturizing product
Bright skin!
Love this it makes my skin feel super moisturized and I feel my skin is more plump and brighter .,, I would definitely recommend this product to someone looking.
Hydrating
[I received this product in exchange for my honest review] I use this product if my skin needs some extra nourishment. I feel like it is very hydrating for my skin but haven't noticed any other benefits but it's in the skincare rotation for me.

Love this!
[I received this product in exchange for my honest review] This stuff is amazing! It has Probiotics and hyaluronic acid and it absorbs nicely into your clean skin leaving your face feeling hydrated, plumped and smoother than ever before. I have noticed significant differences/improvements to my face in photos. Looking forward to a more radiant and youthful appearance with continued use of this product.
Good!
I received this complementary product in exchange of my honest review. Overall, I like the product. It feels nice on my face.