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Summary
Perricone MD Essential Fx Acyl-Glutathione Deep Crease Serum improves the appearance of deep creases, marionette and lip lines.
Benefits
- Highly-potent serum with a silky, luxurious texture absorbs quickly to help smooth the look of even the most stubborn deep lines, wrinkles and creases around the mouth, eyes, lips and forehead, including marionette lines, frown lines, smile lines and nasolabial folds.
- Over time, these engraved imperfections appear more shallow and the look of expression lines improve, as the vitamin F blend works to help nourish the skin’s moisture barrier and protect it from environmental aggressors.
- 93% noticed skin looked renewed*
- 84% saw that skin looked more toned*
- Advanced Claims:
- 89% noticed an improvement in lines and texture*
- 86% felt firmer, tighter skin*
- 86% saw an improvement in expression lines*
- 84% saw that wrinkles were smoothed*
- 83% noticed creases appeared shallower and forehead lines appeared smoother*
- 82% saw tighter-looking skin*
- 80% saw lines smoothed around the mouth and lips*
- 79% noticed engraved imperfections appeared shallower*
- 77% noticed that skin looked lifted*
- 74% felt that skin looked dramatically younger*
- 73% saw that deep-set wrinkles, including marionette lines and nasolabial folds were smoothed*
- *In a consumer study of 102 women after 28 days
Key Ingredients
- Acyl-Glutathione: The Master Antioxidant
- Vitamin F Blend: Ultimate Moisture Barrier Protection
Research Results
- 89% noticed an improvement in lines and fragile skin texture*
- 86% felt firmer, tighter skin*
- 86% saw an improvement in expression lines*
- 84% saw wrinkles were smoothed*
- 83% noticed creases appeared shallower and forehead lines appeared smoother*
- *In a consumer study of 102 women after 28 days.
After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.
Water/Aqua/Eau, Propanediol, Squalane, Hydrogenated Polyisobutene, S-Palmitoylglutathione, Dimethicone, Glycerin, Macadamia Ternifolia Seed Oil, Xylitylglucoside, Tetrahexyldecyl Ascorbate, Caprylic/ Capric Triglyceride, Anhydroxylitol, Phenoxyethanol, Dimethyl MEA, Lactic Acid, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Xanthan Gum, Xylitol, Caprylyl/Capryl Glucoside, Fragrance (Parfum), Linum Usitatissimum (Linseed) Seed Oil, Salvia Hispanica Seed Oil, Tocopherol, Ethylhexylglycerin, Glucose, Tetrasodium Glutamate Diacetate, Glycine Soja (Soybean) Oil, Alaria Esculenta Extract, Magnesium Aspartate, Zinc Gluconate, Sodium Hyaluronate, Ascorbyl Palmitate, Copper Gluconate, Magnesium Chloride, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Potassium Sorbate, Acetyl Hexapeptide-8, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Limonene, Linalool, Hydroxycitronellal, Citronellol.
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Questions
Ask a QuestionQ&A
Showing 3 out of 3 Questions
- Q
Does this product contain retinol
- Asked by Laurie
- Official Answer By PerriconeMD - SamplingHello, This is a not a retinol product. Here is the ingredient list for Deep Crease Serum. INGREDIENTS Water/Aqua/Eau, Propanediol, Squalane, Hydrogenated Polyisobutene, S-Palmitoylglutathione, Dimethicone, Glycerin, Macadamia Ternifolia Seed Oil, Xylitylglucoside, Tetrahexyldecyl Ascorbate, Dimethyl MEA, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-8, Anhydroxylitol, Lactic Acid, Xylitol, Xanthan Gum, Linum Usitatissimum (Linseed) Seed Oil, Salvia Hispanica Seed Oil, Tocopherol, Ethylhexylglycerin, Magnesium Aspartate, Zinc Gluconate, Alaria Esculenta Extract, Glucose, Sodium Hyaluronate, Copper Gluconate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Magnesium Chloride, Caprylic/Capric Triglyceride, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl/Capryl Glucoside, Caprylyl Glycol, Potassium Sorbate, Phenoxyethanol, Fragrance/Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool.Was this answer helpful to you
- Q
Can I use with retinol cream
- Asked by terri
- Official Answer By PerriconeMD - SamplingYes; in fact the two will complement to a retinol cream. We suggest applying the Essential Fx Acyl-Glutathione Deep Crease Serum before our retinol treatment Firming Evening Repair for the best results.Was this answer helpful to you
- Q
Deep smokers lines around lips. Would this product help?
- Asked by Sandi
- Official Answer By PerriconeMD - SamplingThis is an excellent choice of treatment for your concern.Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Best Uses
- 200Daily Use
- 191Fine Lines/Wrinkles
- 59Sensitive Skin
- 40Uneven Skin Tone
- 24Enlarged Pores
Describe Yourself
- 128Beauty Conscious
- 42Beauty Expert
- 36Minimalist
- 10Skin Care Professional
- 168 years young, face ravaged by cancer
Skin Type
- 99Combination
- 68Normal
- 48Dry
- 6Oily
Most Helpful Positive Review
The best serum ever
You would look at women posting their before and after pics and wonder about the depth of their facial creases, their age, life style, nutrition as a factors influencing wrinkles formation and leave the web site in disbelieve I am asking you to believe me cause: I am 62, watching what I am ea...
Most Helpful Critical Review
not as expected
After reading the glowing reviews I purchased the deep crease serum. I really didn't see how it could act as liquid botox but I thought I'd give it a try. I used it twice a day as recommended on my marionette lines and my forehead H crease. Nothing, absolutely nothing. Might work better if you have ...
519 results
Oddly, ineffective
Honestly, ive been using skin care, wrinkle treatments for over 15 years, and this hasnt proven effective or given any visable signs of my smile lines improving.
Will continue to buy over and over
I took one star for the price, it is expensive, even on sale. That being said, it works. I'm 44 and after a hysterectomy forced me into menopause, my skin is not what it was even just a year ago. Fine lines and wrinkles on my forehead, bridge of my nose, and deep creasing beside my nose because I am a side sleeper. I used this product a few years ago, before menopause, just for the expression wrinkles I have on my nose and forehead, and it worked wonders. I decided to try it again and I've only been using it for a week now and I can already see a big difference. I wish I had taken pictures before, because there is definitely a BIG visible difference.
I think it works.
Reviewed at
But I'm not positive. It's hard to compare as I look at my face every day. However the lines above my mouth have almost disappeared. Wish I could see a substantial change in my poor neck but it appears improved. People often say that they can't believe that I am 74.
Disappointed
Reviewed at
I use many products from this line this does absolutely nothing waste of money only botox or surgery is gonna help with deep lines. I will continue to use the other products .not this one
I can't live without this product!
Reviewed at
I used it for the first time over the holidays, and there was a minimal difference at the start. After I use it for about a month I noticed incredible results! I have a deep crease between my eyes on my forehead, and several and unsightly large creases in my neck. I can barely see them now. I think this serum made me look five years younger.