Free standard shipping on any $35 purchase

Use the following zoom and pan buttons to control the image that follows them

Perricone MD Essential Fx Acyl-Glutathione Deep Crease Serum #1
Perricone MD Essential Fx Acyl-Glutathione Deep Crease Serum #1

Tab through the images or use the previous or next buttons to navigate each product image

Perricone MDEssential Fx Acyl-Glutathione Deep Crease Serum

Item 2532645

4.4 out of 5 stars. 516 reviewsQ & A
Size:1.0 oz


Perricone MD Essential Fx Acyl-Glutathione Deep Crease Serum is a serum to smooth deep wrinkles, creases, marionette and lip lines.



  • Softens the look of facial lines from daily repetitive movements
  • Visibly improves etched creases making them appear more shallow
  • Minimizes the appearance of skin imperfections and imparts a beautiful radiance
  • Overall Skin Condition:
  • 93% noticed skin looked renewed*
  • 84% saw that skin looked more toned*
  • Advanced Claims:
  • 89% noticed an improvement in lines and texture*
  • 86% felt firmer, tighter skin*
  • 86% saw an improvement in expression lines*
  • 84% saw that wrinkles were smoothed*
  • 83% noticed creases appeared shallower and forehead lines appeared smoother*
  • 82% saw tighter-looking skin*
  • 80% saw lines smoothed around the mouth and lips*
  • 79% noticed engraved imperfections appeared shallower*
  • 77% noticed that skin looked lifted*
  • 74% felt that skin looked dramatically younger*
  • 73% saw that deep-set wrinkles, including marionette lines and nasolabial folds were smoothed*
  • *In a consumer study of 102 women after 28 days

Key Ingredients

  • Acyl-Glutathione: The Master Antioxidant
  • Vitamin F Blend: Ultimate Moisture Barrier Protection

How To Use

After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.

Shipping & Coupon Restrictions

This brand is excluded from most Ulta Beauty coupons.

See brand eligibility details