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Summary
Highlights
Clinique Smart Night Clinical MD Treatment Retinol Serum is a skin-repairing night treatment that jumpstarts the anti-aging process with retinol plus hydration.
Benefits
- All Skin Types.
- Powered by 0.3% retinol, this creamy formula sinks in to help speed up cell turnover.
- Visibly reduces fine lines and wrinkles.
- Skin tone looks more even, radiant.
- Pores look minimized.
- Delivers instant and lasting hydration, which helps comfort skin and offset dryness sometimes associated with retinol.*
- *Tolerance to retinol varies by person.
- What you should know about retinol:
- Retinol is an extremely effective and powerful anti-aging ingredient. You may experience mild redness, a warm, tingling sensation, or flaking (skin exfoliation). These conditions are normal, temporary indications that the formula is working.
- If you experience increased discomfort when using this product, revert to once every other night until skin adjusts. This adjustment can take up to 4 weeks.
- First time users and those with drier skin types may want to use this product every other night for more than 2 weeks to give skin additional time to adjust.
- For added comfort, use a mild cleanser and layer an additional moisturizer over this product.
- Limit sun exposure in general. Be sure to apply a sunscreen of SPF15 or higher during the day while using this product, and one week after stopping use of it. Note that extreme weather conditions such as wind or cold may be more irritating, so take the proper precautions to protect your face.
- Paraben-free. Phthalate-free.
- No Denatured alcohol. No Synthetic colors.
- SLS-free. SLES-free. Sulfate-free.
- Dermatologist tested.
- Allergy tested. Fragrance-free.
Key Ingredients
- Retinol (0.3%): A pure form of Vitamin A, it's an effective anti-aging ingredient known to help visibly reduce lines and wrinkles, minimize the appearance of pores, and smooth and refine texture.
- Youth-Boosting Blend: Helps skin look smoother. Includes acetyl hexapeptide-8, niacinamide, sigesbeckia extract, and ascorbic acid.
- Comforting Hydrator Blend: Helps infuse skin with hydration. Includes hyaluronic acid, mango seed butter, wheat and barley extract, coffee seed oil, squalane, and vitamin E.
Research Results
- Clinical Testing:
- Restores radiance with 1 use.
- Minimizes the appearance of pores in 7 days.
- Skin feels smoother in 28 days/4 weeks.
- Improves evenness of skin tone in 8 weeks.
- Retexturizes skin in 12 weeks.
- Provides instant and lasting hydration.
- With continued use, visibly reduces lines and wrinkles.
Item 2572793
Apply pea size amount (0.25g) of retinol at night. Avoid eye area. Tip: For first two weeks, use every other night, then nightly. Use sunscreen and limit sun exposure while using and the week after. Do not use with other retinol products, such as Clinique Fresh Pressed Overnight Booster with Pure Vitamin A (Retinol).
To help optimize the results of retinol, we suggest using as part of a regimen with other anti-aging products, such as:
- In AM: Clinique Smart Custom-Repair Serum + Clinique Smart SPF 15 Custom-Repair Moisturizer
- In PM: Clinique Smart Custom-Repair Serum + Clinique Smart Night Retinol + Clinique Smart Clinical MD Resculpt or Revolumize or Clinique Smart Night Custom-Repair Moisturizer (for added comfort if needed).
Water\Aqua\Eau, Caprylic/Capric Triglyceride, PPG-15 Stearyl Ether, C12-20 Acid PEG-8 Ester, Glycerin, Niacinamide, Phenyl Trimethicone, Caprylic/Capric/Myristic/Stearic Triglyceride, Algae Extract, Dimethicone, Hydroxyethyl Urea, Cetyl Alcohol, Retinol, Sigesbeckia Orientalis (St. Paul'S Wort) Extract, Mangifera Indica (Mango) Seed Butter, Coffea Arabica (Coffee) Seed Oil, Sodium Hyaluronate, Caffeine, Ascorbic Acid, Urea, Butylene Glycol, Squalane, Trehalose, Triticum Vulgare (Wheat) Germ Extract, Tocopheryl Acetate, PEG-100 Stearate, Linoleic Acid, Glyceryl Stearate, Hordeum Vulgare (Barley) Extract\Extrait D'Orge, Acetyl Hexapeptide-8, Sorbitol, Potassium Cetyl Phosphate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Behenyl Alcohol, Sodium Pca, Sodium Hydroxide, Caprylyl Glycol, Carbomer, Triacetin, Polyquaternium-51, Xanthan Gum, BHT, Disodium EDTA, Sodium Metabisulfite, Chlorphenesin, Potassium Sorbate, Phenoxyethanol.
Please be aware that ingredient lists may change or vary from time to time. Please refer to the ingredient list on the product package you receive for the most up to date list of ingredients.
This brand is excluded from most Ulta Beauty coupons.
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Questions
Ask a QuestionQ&A
Showing 5 out of 10 Questions
- Q
What percent is this product
- Asked by Mary
- Official Answer By Clinique USWe're glad you asked! Clinique Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol, which contains Retinol (0.3%), a pure form of Vitamin A as an effective anti-aging ingredient known to help visibly reduce lines and wrinkles, minimize the appearance of pores, and smooth and refine texture. Retinol is an extremely effective and powerful anti-aging ingredient. We do not recommend using two retinol products together. Be sure you are limiting sun exposure while using, and for at least one week after. Visit our store, and a Beauty Associate will offer personalized application tips. We'd love to hear your feedback!Was this answer helpful to you
- Q
Do you have a night cream moisturizer
- Asked by T
- Official Answer By Clinique USWe are so happy you asked! We have a great moisturizer for nighttime use that works perfectly with this serum. Clinique's Smart Clinical Repair Wrinkle Correcting Cream visibly repairs lines and wrinkles, hydrates and strengthens. Visit us in-store at your nearest Ulta to experience this moisturizer!Was this answer helpful to you
- Q
You recommend using clinique smart night moisturizer after using this product, however that is no longer available on your website. Will you be bringing this back? I was told to use this in place of the moisturizer at night. This is frustrating.
- Asked by Patty
- Official Answer By Clinique USThanks for asking, we never want our fans frustrated! Clinique Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol Serum, as a serum, should be followed by your favorite Clinique moisturizer after. We like Clinique Smart Clinical Repair Wrinkle Correcting Cream (or Rich Cream for those that need deep hydration). This moisturizer may be used in place of the retired Clinique Smart Night Custom-Repair Moisturizer. When using the serum, for the first two weeks, only use it every other night, then nightly. Remember to always use sunscreen and limit sun exposure while using and the week after.Was this answer helpful to you
- Q
Do I moisturize before or after?
- Asked by donkey mom
- Official Answer By Clinique USWe're so glad you asked! Apply your moisturizer after Clinique Smart Night Clinical MD Multidimensional Repair Treatment Retinol. We recommend Clinique Smart Clinical MD Multi-Dimensional Age Transformer Resculpt or Revolumize or Clinique Smart Night Custom-Repair Moisturizer. Enjoy!Was this answer helpful to you
- Q
Can I use this with the night time turn around cream?
- Asked by Laura
- Official Answer By Clinique USThank you for your question. We recommend using Clinique Smart Nigth Clinical MD Multi-Dimensional Repair Treatment Retinol with Clinique Smart Night Custom-Repair Moisturizer, which helps skin attract and retain moisture and gives skin an extra boost of repair while you sleep. We can't wait to hear what you think! Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Skin Type
Most Helpful Positive Review
Excellent!
The negative reviews of this product surprise me and that some are saying that the directions are not clear. Any time one uses a Retinol product, you HAVE to apply a moisturizer over it. If you don't, you will end up with red, dry, painful skin. The directions on the pkg insert as well as here under...
Most Helpful Critical Review
Too intense for my dry and sensitive skin
I used this product as directed and had to discontinue it before I even made it out of the two week period where you only use it every other day. As a disclaimer I wasn't even going outside (thanks COVID) so it wasn't like I got a bunch of sun and messed myself up. I really did use it as directed. ...
111 results
When will this be back in stock?
Verified Reviewer
Reviewed at

I love this product but have been out of it for two months now! When will it be back in stock?
I would not buy this product again
I returned this product after a few days. My skin was irritated and my face was swollen.
Had to use carefully due to irritation
Verified Reviewer
Reviewed at

I have rosacea prone skin and bought this product to get acclimated to using retinol for the first time since it has .03%. Their other retinol has .1%, so I thought this one would be more gentle. I was wrong! I used it once a week for a while and then every few days, I used it on top of a layer of moisturizer followed by more moisturizer… despite my careful application I was still getting some redness and peeling months later. It did get gradually better for me though as I adjusted, but I never quite knew what my skin would look like the following day. I tried out their other (stronger) retinol because I had already bought it and to my surprise my skin has tolerated it much better than this one. It is a lighter formula. This one is thicker. I like that it has niacinimide though, the other one doesn't.
Makes my skin feel revitalized!
Verified Reviewer
Reviewed at

I love this product and use religiously along with my other Clinique regimen. It's not greasy, just a little goes a long way.
Fantastic spot treatment for acne flare ups!
Verified Reviewer
Reviewed at

I have used this in the past as an all over treatment but, because I'm not as diligent as I should be I discontinued using it for that purpose. However, it is fantastic as a spot treatment for acne or pimples. If I see that I'm getting a flare up, I put a tiny amount over the area before I goto bed and the next morning it's gone! I much prefer this to the acne gel because it's an instantaneous fix. Clinique really should include this in the description because a lot of people may start using it for that reason alone. My opinion, buy it and keep it on hand because you never know when you may need it.