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Summary
Highlights
ma:nyo Bifida Biome Complex Ampoule fortifies the skin barrier. It visibly plumps and nourishes skin's moisture barrier for lasting hydration.
Features
- Bifida that focuses on skin nourishing, creating a balanced skin barrier and lasting hydration while improving skin tone after constant usage.
- Builds a strong foundation for the skin and protect it to make it healthy and firm
- Experience the power with healthy skin layer and strong moisture barrier to prevent future breakouts.
Key Ingredients
- Bifida Biome - Builds up the skin's barrier and keeps well-balanced skin condition.
- 10 Types of Hyaluronic Acid - Penetrates through the skin and fill in every gap between skin layers for ample hydration.
- 5 Probiotics - Strengthens the skin's barrier and helps the skin restore its original complexion.
Formulated Without
- Fragrance
- Silicon
- Paraben
Item 2626987
- Drip 3-5 drops evenly across the face, avoid the eye contour and contact with eyes.
- Lighly massage the ampoule into the skin in a circular motion.
- Finish by gently patting the skin until the essence is fully absorbed.
Bifida Ferment Lysate, Butylene Glycol, Bifida Ferment Filtrate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate, Saccharomyces Ferment Filtrate, Glycerin, Niacinamide, 1,2-Hexanediol, Lactobacillus/Pumpkin Fruit Ferment Filtrate, Aureobasidium Pullulans Ferment, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Leontopodium Alpinum Callus Culture Extract, Cutibacterium Granulosum Ferment Extract Filtrate(5,000ppm), Asiaticoside, Asiatic Acid, Madecassic Acid, Pentylene Glycol, Squalane, Hydrogenated Lecithin, Copper Tripeptide-1, Tromethamine, Acetyl Hexapeptide-8, Propanediol, Ethylhexylglycerin, Dextrin, Water, Caffeine, Benzyl Glycol, Sodium Phytate, Hydrolyzed Algin, Xanthan Gum, Epigallocatechin Gallate, Carbomer, Physalis Alkekengi Calyx Extract, Hydrolyzed Glycosaminoglycans, Polyglyceryl-10 Laurate, Theobroma Cacao (Cocoa) Seed Extract, Adenosine.
Free gift with purchase
Free gift with purchase
Free 3 piece gift with $35 skincare purchase (valid thru 8.2.25 on in store or shipped purchases. Full or partial pickup or same day delivery purchases do not qualify. While quantities last and subject to in store availability)
Free gift with purchase
Free double cleansing set with $20 Ma:nyo purchase (valid thru 7/26/25 on in store or shipped purchases. Full or partial pickup or same day delivery purchases do not qualify. While quantities last and subject to in store availability)
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Questions
Ask a QuestionQ&A
Showing 5 out of 10 Questions
- Q
Can i use this alongside the tir tir toner or should i use one or the other?
- Asked by Hek1996
- Official Answer By ma:nyo - Brand EngageDear Customer, Yes, you can use both. Apply the TIRTIR toner first, then follow with the ma:nyo ampoule. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
What is the order of using this product with my Vitamin C serum abs also my Retinoid cream?
- Asked by DB
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! We recommend using your Vitamin C serum in the morning, followed by the ma:nyo Bifida Biome Complex Ampoule. In the evening, apply the ampoule before your retinoid cream. It helps to hydrate and soothe the skin, making it a great buffer between active ingredients.If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Would I use this product before or after my vit c serum in the morning?
- Asked by DBO
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! In the morning, apply your Vitamin C serum first, then follow with the ma:nyo Bifida Biome Complex Ampoule. This helps lock in hydration and support your skin barrier. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Can i use a vitamin C serum with this ampoule? If so, should the serum or ampoule be applied first? Can i apply one product immediately after the other, or do i need to wait for the PH to balance?
- Asked by Old
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You may use a Vitamin C serum with the ma:nyo Bifida Biome Complex Ampoule. Apply the Vitamin C serum first, followed by the ampoule. There’s no need to wait between steps—both can be applied one after the other. The ampoule helps soothe and hydrate the skin, making it a great pairing with active ingredients like Vitamin C. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
- Q
Do I need a toner prior to use or can I just use a moisturizer after applying this product to my skin?
- Asked by Rose
- Official Answer By ma:nyo - Brand EngageDear Customer, Thank you for reaching out! You can use ma:nyo Bifida Biome Complex Ampoule after toner. Using a toner can help prep your skin and boost absorption. If you have any other questions, feel free to ask—we’re always happy to help!Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Most Helpful Positive Review
High quality hydration at a sensible price!
[I received this product in exchange for my honest review] After consistent use, the Manyo Bifida Biome Complex Ampoule has earned a permanent spot in my skincare routine — and here's why. ✨ Texture & Application The ampoule has a lightweight, serum-like texture that absorbs quickly without leaving...
Most Helpful Critical Review
Healthy, Balanced, and Calm: My Experience with ma:nyo Bifid
I've been using the ma:nyo Bifida Biome Complex Ampoule consistently and it has honestly become one of my favorite steps in my skincare routine. The texture is lightweight but still feels nourishing, and it layers really well with other products without any pilling or stickiness. What I really appr...
246 results
Where do I start?
[I received this product in exchange for my honest review] This product has been added to my daily routine! It is the perfect consistency and finish for my oily combo skin. There are no strong scents and residue left. This product does go a long way as well and the packaging is great quality! I am super impressed and will be buying again as I continue to see a clear and strong improvement in my skin! Thank you for this complimentary product!
Healthy, Balanced, and Calm: My Experience with ma:nyo Bifid
I've been using the ma:nyo Bifida Biome Complex Ampoule consistently and it has honestly become one of my favorite steps in my skincare routine. The texture is lightweight but still feels nourishing, and it layers really well with other products without any pilling or stickiness. What I really appreciate about this ampoule is how it helps strengthen and calm my skin barrier. After a few weeks of use, my skin started to look more balanced — less redness, fewer random dry patches, and an overall healthier appearance. It's also great for days when my skin feels a little stressed or reactive. It gives that extra boost of hydration and comfort without clogging pores or feeling heavy. Another thing I've noticed is how much smoother and plumper my skin looks in the morning. It seems to help with maintaining elasticity and keeping my skin looking fresh and well-rested. I also like knowing it's working behind the scenes to support my skin's natural microbiome. Overall, this is one of those products that's gentle but really effective over time. It's not flashy, but it delivers steady, visible results. I'm definitely planning to keep it in my rotation.
Love!
[I received this product in exchange for my honest review] The bifida biome complex ampoule by Ma:nyo is truly fantastic! My skin felt more hydrated and happy after even the first use! The texture is wonderful- smooth and even, not sticky at all. There is ZERO scent, which I greatly prefer in skincare. I love that the bottle is frosted so it protects the serum's ingredients and integrity. All in all, a win for me!
Light and effective!
I received this product for free from Ulta and ma:nyo in exchange for my honest review. So far, I am really enjoying this serum and love how quickly my skin absorbs it. I feel that it is making my skin glow without the sticky residue of some serums. It is yet very effective. The scent is gentle and not overwhelming. I'll definitely continue using this in my daily regime.
Hydrating, calming, and great for barrier repair!
[I received this product in exchange for my honest review] I've been using the ma:nyo Bifida Biome Complex Ampoule for a few weeks, and it's been a game changer for my skin. It instantly hydrates and makes my skin feel plump and soothed, especially when it's feeling sensitive or irritated. I love the lightweight texture — it absorbs quickly without feeling sticky. I've noticed fewer breakouts and my overall skin tone looks healthier and more even. Great for acne-prone or dehydrated skin. Highly recommend if you're looking to strengthen your skin barrier!
