Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
Summary
Nioxin Pro Clinical's System Kit 2 is designed for natural, untreated hair with progressed thinning. Clinically and dermatologically tested, this shampoo nourishes and gently cleanses your hair to prevent against follicle-clogging sebum, resulting in thicker, fuller hair.
Benefits
- Thickens the hair: Nioxin System Kit 2 is clinically designed to add thickness and fullness to natural hair with progressed thinning, with visible results in just 30 days.
- Nourishes the scalp: Infused with nourishing botanicals, antioxidants, and UV protecting ingredients, this kit's Scalp + Hair Thickening Treatment can nourish and revitalize the scalp, improving its overall health and condition.
Research Results
- 85% of consumers noticed a thickening effect, 80% noticed an increase in hair density, 80% noticed an increase in hair fullness
Disclaimers
- *Based on a survey among 230 U.S. panelists concerned about thinning hair who tried the systems (each tested 1 system kit), conducted by SIRS, 2016
Item 2623201
Apply shampoo to scalp and massage evenly. Rinse thoroughly.
Pre-caution: Do not get into the eyes. Keep out of reach of children. For any questions or concerns about side effects, always consult a medical professional.
Aqua/Water/Eau, Sodium Laureth Sulfate, Sodium Lauryl Sulfate, Cocamidopropyl Betaine, Cocamide MEA, Sodium Benzoate, Citric Acid, Sodium Chloride, Salicylic Acid, Mentha Arvensis Leaf Oil, Mentha Piperita (Peppermint) Oil, Tetrasodium EDTA, Methylparaben, Propylene Glycol, Glycerin, Sodium Hydroxide, Limonene, Camellia Sinensis Leaf Extract, Cystine Bis-PG-Propyl Silanetriol, Niacinamide, Panthenol, Biotin, Lecithin, Tocopheryl Acetate, Urtica Dioica (Nettle) Leaf Extract, Humulus Lupulus (Hops) Flower Extract, Citrus Paradisi (Grapefruit) Peel Extract, Yellow 5 (CI 19140), Vaccinium Myrtillus Leaf Extract, Acer Saccharum (Sugar Maple) Extract, Saccharum Officinarum/Sugar Cane Extract/Extrait de canne à sucre, Citrus Limon (Lemon) Peel Extract, Faex Extract/Yeast Extract/Extrait de levure, Propylparaben, Blue 1 (CI 42090), Phenoxyethanol, Citrus Aurantium Dulcis (Orange) Fruit Extract, Red 33 (CI 17200), Potassium Sorbate, Maltodextrin, Sodium Citrate, Ethylparaben, Butylparaben, Sodium Xylenesulfonate.
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Questions
Ask a QuestionQ&A
Showing 20 out of 321 Questions
- Q
where is this product manufactured ??
- Asked by Kathy
- Official Answer By Nioxin - Brand EngageNioxin products come from Guanajuato, MexicoWas this answer helpful to you
- Q
Is quality good
- Asked by Sam
- Official Answer By Nioxin - Brand EngageYes, very good qualityWas this answer helpful to you
- Q
Is this gluten free?
- Asked by Cancer gal
- Official Answer By Nioxin - Brand EngageNioxin is free of gluten. Even though the products may not have gluten in the formulation we are not able to claim "Gluten-Free" as it can come in contact with other products or ingredients such as gluten in manufacturing. Be aware aware if you are sensitive to gluten you could have a reaction. Maltodextrin is found in Nioxin products and can be considered Gluten Free as it has no relation to Barley or Wheat.Was this answer helpful to you
- Q
How to use scalp care nioxin 2
- Asked by Mmm
- Official Answer By Nioxin - Brand EngageUSAGE INSTRUCTIONS Step 1: Apply shampoo to scalp and massage evenly. Rinse thoroughly. Step 2: Rub condition from root to ends. Rinse thoroughly. Step 3: Apply treatment to scalp and hair, at the roots of towel dried hair. Do not rinse. Use the complete system daily for visible results.Was this answer helpful to you
- Q
Does this product contain sulfates
- Asked by JLC
- Official Answer By Nioxin - Brand EngageYes, there are sulfates in the shampoo. Sulfates have recently gotten a bad rap as being bad for you and your hair. What you need to know is that sulfates are the ingredient that cleanses the hair. One would need to consume a large quantity of them to have negative results. We use only the highest-grade sulfates – which provide cleansing necessary without pulling color or damaging the hair. Optimal levels are contained in our products which leave the hair clean without over drying. We offer a very nourishing formula overall, which is gentle on the skin and hair. The SLS (sulfates) used are in the international regulatory permitted range, they have been tested extensively for decades to ensure customer health and safety. Most of what we hear is a myths that come from a "sulfate free" marketing campaign or company. Harsh sulfates will most likely always pull color from the hair and cause dryness. Gentle sulfates with the proper formulation of other ingredients will keep hair color in longer than most sulfate free shampoos. Sulfate free shampoos most often do not cleanse the hair thoroughly enough to rid it of dirt, oils, product and environmental debris. This causes more dirt to attach to the hair and the formation of free radicals. Free radicals cause the fading of hair color. To protect color treated hair we have the Pro-Color Shield technology that prolongs hair color. The relationship between sulfates and hair color is not straight forward. The appearance of a sulfate in a shampoo does not automatically determine the "safeness" of the product. All of our products are tested extensively to ensure their safety for consumer use. I hope that this helps. If you have, further questions please call 800-935-5273.Was this answer helpful to you
- Q
Does this leave roots oily?
- Asked by Michele
- Official Answer By Nioxin - Brand EngageIf used as directed it does not leave residue on the scalp. Use only on a damp scalp- towel dried scalp -on the days you wash your hair. Shake and apply 2-4 pumps massage onto scalp. Then style as usual.Was this answer helpful to you
- Q
When I use this after shampooing, the System 2 Leave on Treatment makes my hair gummy. Can I apply it to unwashed hair as an overnight treatment the night before shampooing?
- Asked by Susan
- Official Answer By Nioxin - Brand EngageIt sounds like you are using way to much scalp treatment. Use after washing on a slightly damp scalp massage 2-4 pumps into the scalp, and style as usual.Was this answer helpful to you
- Q
Will this help with thinning hair due to age , I am 72 , have tried a number of products that claim to help with thinning hair but none have worked for me . Could it be due to my age ?
- Asked by Old Lady Locks
- Official Answer By Nioxin - Brand EngageSystem Kits are the ideal starting point for a healthier hair journey. They're designed to create the optimal environment for hair growth by: Cleansing: Effectively removing buildup from hair follicles. Stimulating: Enhancing scalp circulation. Nourishing: Providing antioxidants and botanicals to support hair and scalp health. Hair loss can have various causes, including age, genetics, health conditions, diet, and environmental factors. For a personalized assessment of your hair loss, we recommend consulting with a physician or a qualified trichologist. We believe in a holistic approach to hair health. Nioxin System Kits offer a comprehensive solution to address common hair concerns.Was this answer helpful to you
- Q
What is the difference between System 3 and System 4? Both say for the same types of hair.
- Asked by Felicia
- Official Answer By Nioxin - Brand EngageThese two systems are meant for the same hair type. The difference is that system 3 is for normal to thin looking hair, while 4 is for noticeably thinning hair.Was this answer helpful to you
- Q
Can this be used on color treated hair? Will this affect the color of hair?
- Asked by Eve
- Official Answer By Nioxin - Brand EngageThe system 2 does not have the color protectant in it like the system 4 does. It will not harm your hair in any way to use system 2, just know that it is not protecting the color.Was this answer helpful to you
- Q
If I shower every night is it okay to keep it on for that long, or do you guys recommend a certain time period.
- Asked by IH
- Official Answer By Nioxin - Brand EngageThat is great. The Scalp Treatment is a leave-in Treatment Only use on days that you shower, even if you only shower twice a week, it is safe to leave-in.Was this answer helpful to you
- Q
Is this okay to use with a water softener system?
- Asked by Jane S.
- Official Answer By Nioxin - Brand EngageYesWas this answer helpful to you
- Q
Follow up on the usage with something like minoxidil - why does the scalp treatment counter it? I'm trying to figure out the science, and if it's problematic if there is an "add-on" that will help replace it (or the primary active ingredient) in the overall system where you can still also benefit from the use of a product like Rogaine at the same time.
- Asked by Bastain L.
- Official Answer By Nioxin - Brand EngageIt is not recommended to use this product with Rogain. The Scalp Treatment is not medicated (like rogain is) so there isnt an active ingredientWas this answer helpful to you
- Q
Hi two part question: can i use this daily? can you explain why minoxidil and this cancel each other out if I use this in the morning and Minoxidil at night.
- Asked by Thomas
- Official Answer By Nioxin - Brand EngageYes, the scalp and hair treatment can be used daily (only if shampooing daily). The Minoxidil and Scalp Treatment will not work properly if used together, even at altering times a day. Additionaly there is an increased risk of scalp irritation when pairing the products.Was this answer helpful to you
- Q
Where can I get 16oz size of Nioxin 2
- Asked by Terrys hair
- Official Answer By Nioxin - Brand EngageSo that we may provide you with the most up-to-date pricing and promotions info, please contact us at gethelp@ulta.com for help. Thanks!Was this answer helpful to you
- Q
Can this product be used in conjunction with minoxidil?
- Asked by Six
- Official Answer By Nioxin - Brand EngageThe shampoo and conditioner may be used with minoxidil. The scalp and hair treatemtn and minoxidil cancel one another out even if used at differing times in the day.Was this answer helpful to you
- Q
Can this be used with rosemary oil?
- Asked by Lyz
- Official Answer By Nioxin - Brand EngageWe do not test our products with rosemary oil. Additonal oils may clog the hair follicles and cause the Nioxin to be ineffective.Was this answer helpful to you
- Q
Is this cruelty free? Peta or Leaping Bunny? I only support cruelty free products. If sold in countries like china, it is NOT cruelty Free . I understand laws, but animals do not have to be tortured for any reason ! Especially beauty products . I Hope this is certified Cruelty Free. Would llike to purchase
- Asked by Debbie
- Official Answer By Nioxin - Brand EngageAt Wella Company, we do not test our products on animals and are committed to ending animal testing across the beauty industry. All our products are safe and have been developed, manufactured and packaged in compliance with the laws, regulations, and guidelines that are applicable in each country in which we sell them. Some governments or agencies stipulate the testing of finished products on animals in accordance with local legal and regulatory requirements.Was this answer helpful to you
- Q
Does not say how many ounces in each full size bottle. Specific information please
- Asked by Beck
- Official Answer By Nioxin - Brand Engageshampoo and conditioner are 10.1oz Scalp Treatment is 3.4Fl ozWas this answer helpful to you
- Q
My hair is natural, undyed, very fine which causes a lot of frizz, it falls out a lot, I don't know what number I should use? My roots are oily and my ends are dry!
- Asked by Emily
- Official Answer By Nioxin - Brand EngageNioxin Hair Fall Defense Shampoo removes build-up and is clinically proven to grow¹ stronger hair from the root. 93% of people have visibly less hair fall in 12 weeks². The shampoo deeply cleanses your scalp, removing impurities and excess oil. It's formulated with a powerful blend of niacinamide, caffeine, lauric acid and SANDALORE™. Together, these ingredients work to help stimulate hair follicles and nourish the hair. To use, massage shampoo on to scalp & hair for 2 minutes. Rinse thoroughly. Use daily for best results. ¹Not a hair regrowth product. ²After a 12 week clinical study among 30 consumers with hair loss. or Nioxin system kits are formulated for certain hair types. Please use the following information to figure out which system is right for you. Normal to thin looking hair System 1- Formulated for natural, untreated hair with light thinning System 3- Formulated for dry, damaged, coarse, or colored hair with light thinning Noticeably thinning hair- has UV protection as an added benefit System 2- Formulated for natural, untreated hair with progressed thinning System 4- Formulated for dry, damaged, coarse, or colored hair with progressed thinning Please call Nioxin Technical support at 800-935-5273 for additional information and product recommendations.Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
My Beauty Routine Takes
Best Uses
Describe Yourself
Gender
Hair Type
Most Helpful Positive Review
Great product for my thinning hair problem
I've been using this product for 2 weeks and use the complete system for natural thinning hair. I've noticed little to no hair loss and my daughter says that the problem areas are really improving. It is not feasible for me to wash my hair daily; therefore I wash it every other day. I leave the l...
Most Helpful Critical Review
more hair shedding
I have thinning hair in the frontal region. My hair part isn't noticeably thinning, but it could be better. I attribute my hair loss to genetics. It started in my teens so i've tried several products and topical medications to ease reduce the rate of shedding, and possibly to regrow hair as well. Ba...
799 results
It really worked!
I was skeptical about whether this would work and tried other hair serums that were more expensive and pills but nothing really worked. I bought the shampoo and conditioner in april 2025 and for a while I wasnt seeing much difference. Im glad I didnt give up though and when I was looking at my hairline the orher day, I noticed all this new baby hair growth on the thinning sections on both the left and right top of my scalp. I'm not sure if it would work for large patches, but it worked for me. Excited to see how it will look once they fully grow in! It's not cheap, but the large bottle lasts several months and its still more affordable than pills and doesnt require putting extra stuff in your hair after you shower.
STAY AWAY!!!
Hair Type Straight Hair
SOMETHING has changed... I have been using this stuff for years (#2 system) and my last purchase from Ulta is a different formula or has production issues... The pump top treatment is a foam that quickly turns to liquid. It used to not be so runny. It immediately ran down my face and caused a horrible and painful rash/burn. I have never experienced this before with the #2 system. Ulta please look into this product, it's dangerous!

Yes
Hair Type Very Curly Hair
Love this product
Will purchase this product again.
Hair Type Wavy Hair
Great product!
I will most definitely buy this product again!
Hair Type Straight Hair
This product did exactly what I wanted.. no more thin hair for this gal!