Use the following zoom and pan buttons to control the image that follows them
Tab through the images or use the previous or next buttons to navigate each product image
Offers
(2)
Summary
Highlights
Clinique Smart Night Clinical MD Treatment Retinol Serum is a skin-repairing night treatment that jumpstarts the anti-aging process with retinol plus hydration.
Benefits
- All Skin Types.
- Powered by 0.3% retinol, this creamy formula sinks in to help speed up cell turnover.
- Visibly reduces fine lines and wrinkles.
- Skin tone looks more even, radiant.
- Pores look minimized.
- Delivers instant and lasting hydration, which helps comfort skin and offset dryness sometimes associated with retinol.*
- *Tolerance to retinol varies by person.
- What you should know about retinol:
- Retinol is an extremely effective and powerful anti-aging ingredient. You may experience mild redness, a warm, tingling sensation, or flaking (skin exfoliation). These conditions are normal, temporary indications that the formula is working.
- If you experience increased discomfort when using this product, revert to once every other night until skin adjusts. This adjustment can take up to 4 weeks.
- First time users and those with drier skin types may want to use this product every other night for more than 2 weeks to give skin additional time to adjust.
- For added comfort, use a mild cleanser and layer an additional moisturizer over this product.
- Limit sun exposure in general. Be sure to apply a sunscreen of SPF15 or higher during the day while using this product, and one week after stopping use of it. Note that extreme weather conditions such as wind or cold may be more irritating, so take the proper precautions to protect your face.
- Paraben-free. Phthalate-free.
- No Denatured alcohol. No Synthetic colors.
- SLS-free. SLES-free. Sulfate-free.
- Dermatologist tested.
- Allergy tested. Fragrance-free.
Key Ingredients
- Retinol (0.3%): A pure form of Vitamin A, it's an effective anti-aging ingredient known to help visibly reduce lines and wrinkles, minimize the appearance of pores, and smooth and refine texture.
- Youth-Boosting Blend: Helps skin look smoother. Includes acetyl hexapeptide-8, niacinamide, sigesbeckia extract, and ascorbic acid.
- Comforting Hydrator Blend: Helps infuse skin with hydration. Includes hyaluronic acid, mango seed butter, wheat and barley extract, coffee seed oil, squalane, and vitamin E.
Research Results
- Clinical Testing:
- Restores radiance with 1 use.
- Minimizes the appearance of pores in 7 days.
- Skin feels smoother in 28 days/4 weeks.
- Improves evenness of skin tone in 8 weeks.
- Retexturizes skin in 12 weeks.
- Provides instant and lasting hydration.
- With continued use, visibly reduces lines and wrinkles.
Item 2572793
Apply pea size amount (0.25g) of retinol at night. Avoid eye area. Tip: For first two weeks, use every other night, then nightly. Use sunscreen and limit sun exposure while using and the week after. Do not use with other retinol products, such as Clinique Fresh Pressed Overnight Booster with Pure Vitamin A (Retinol).
To help optimize the results of retinol, we suggest using as part of a regimen with other anti-aging products, such as:
- In AM: Clinique Smart Custom-Repair Serum + Clinique Smart SPF 15 Custom-Repair Moisturizer
- In PM: Clinique Smart Custom-Repair Serum + Clinique Smart Night Retinol + Clinique Smart Clinical MD Resculpt or Revolumize or Clinique Smart Night Custom-Repair Moisturizer (for added comfort if needed).
Water\Aqua\Eau, Caprylic/Capric Triglyceride, PPG-15 Stearyl Ether, C12-20 Acid PEG-8 Ester, Glycerin, Niacinamide, Phenyl Trimethicone, Caprylic/Capric/Myristic/Stearic Triglyceride, Algae Extract, Dimethicone, Hydroxyethyl Urea, Cetyl Alcohol, Retinol, Sigesbeckia Orientalis (St. Paul'S Wort) Extract, Mangifera Indica (Mango) Seed Butter, Coffea Arabica (Coffee) Seed Oil, Sodium Hyaluronate, Caffeine, Ascorbic Acid, Urea, Butylene Glycol, Squalane, Trehalose, Triticum Vulgare (Wheat) Germ Extract, Tocopheryl Acetate, PEG-100 Stearate, Linoleic Acid, Glyceryl Stearate, Hordeum Vulgare (Barley) Extract\Extrait D'Orge, Acetyl Hexapeptide-8, Sorbitol, Potassium Cetyl Phosphate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopherol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Behenyl Alcohol, Sodium Pca, Sodium Hydroxide, Caprylyl Glycol, Carbomer, Triacetin, Polyquaternium-51, Xanthan Gum, BHT, Disodium EDTA, Sodium Metabisulfite, Chlorphenesin, Potassium Sorbate, Phenoxyethanol.
Please be aware that ingredient lists may change or vary from time to time. Please refer to the ingredient list on the product package you receive for the most up to date list of ingredients.
This brand is excluded from most Ulta Beauty coupons.
We think you'll like
12 items
Use previous and next buttons to navigate the slides of the We think you'll like Product Carousel
Similar items for you
12 items
Use previous and next buttons to navigate the slides of the Similar items for you Product Carousel
Sponsored products
12 items
Use previous and next buttons to navigate the slides of the Sponsored products Product Carousel
Questions
Ask a QuestionQ&A
Showing 5 out of 10 Questions
- Q
What percent is this product
- Asked by Mary
- Official Answer By Clinique USWe're glad you asked! Clinique Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol, which contains Retinol (0.3%), a pure form of Vitamin A as an effective anti-aging ingredient known to help visibly reduce lines and wrinkles, minimize the appearance of pores, and smooth and refine texture. Retinol is an extremely effective and powerful anti-aging ingredient. We do not recommend using two retinol products together. Be sure you are limiting sun exposure while using, and for at least one week after. Visit our store, and a Beauty Associate will offer personalized application tips. We'd love to hear your feedback!Was this answer helpful to you
- Q
Do you have a night cream moisturizer
- Asked by T
- Official Answer By Clinique USWe are so happy you asked! We have a great moisturizer for nighttime use that works perfectly with this serum. Clinique's Smart Clinical Repair Wrinkle Correcting Cream visibly repairs lines and wrinkles, hydrates and strengthens. Visit us in-store at your nearest Ulta to experience this moisturizer!Was this answer helpful to you
- Q
You recommend using clinique smart night moisturizer after using this product, however that is no longer available on your website. Will you be bringing this back? I was told to use this in place of the moisturizer at night. This is frustrating.
- Asked by Patty
- Official Answer By Clinique USThanks for asking, we never want our fans frustrated! Clinique Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol Serum, as a serum, should be followed by your favorite Clinique moisturizer after. We like Clinique Smart Clinical Repair Wrinkle Correcting Cream (or Rich Cream for those that need deep hydration). This moisturizer may be used in place of the retired Clinique Smart Night Custom-Repair Moisturizer. When using the serum, for the first two weeks, only use it every other night, then nightly. Remember to always use sunscreen and limit sun exposure while using and the week after.Was this answer helpful to you
- Q
Do I moisturize before or after?
- Asked by donkey mom
- Official Answer By Clinique USWe're so glad you asked! Apply your moisturizer after Clinique Smart Night Clinical MD Multidimensional Repair Treatment Retinol. We recommend Clinique Smart Clinical MD Multi-Dimensional Age Transformer Resculpt or Revolumize or Clinique Smart Night Custom-Repair Moisturizer. Enjoy!Was this answer helpful to you
- Q
Can I use this with the night time turn around cream?
- Asked by Laura
- Official Answer By Clinique USThank you for your question. We recommend using Clinique Smart Nigth Clinical MD Multi-Dimensional Repair Treatment Retinol with Clinique Smart Night Custom-Repair Moisturizer, which helps skin attract and retain moisture and gives skin an extra boost of repair while you sleep. We can't wait to hear what you think! Was this answer helpful to you
Reviews
Write A REVIEWReview Snapshot
by PowerReviews
Ratings Distribution
Skin Type
Most Helpful Positive Review
Excellent!
The negative reviews of this product surprise me and that some are saying that the directions are not clear. Any time one uses a Retinol product, you HAVE to apply a moisturizer over it. If you don't, you will end up with red, dry, painful skin. The directions on the pkg insert as well as here under...
Most Helpful Critical Review
Too intense for my dry and sensitive skin
I used this product as directed and had to discontinue it before I even made it out of the two week period where you only use it every other day. As a disclaimer I wasn't even going outside (thanks COVID) so it wasn't like I got a bunch of sun and messed myself up. I really did use it as directed. ...
111 results
High Hope
Verified Reviewer
Reviewed at

I just started using this product and I really like how it makes my skin feel. I haven't been using it long enough to see results right now but have high hopes for good results soon.
Love this retinol product!
Verified Reviewer
Reviewed at

Love this product. My skin adapted to this retinol quickly as it has a lot of moisturizing benefits to it as well. Definitely has made my skin look smoother and has pulled out some trouble spots and got rid of them quickly too.
Smoothens lines with a small application
Verified Reviewer
Reviewed at

I use this sparingly a few times a night to alternate with the wrinkle correcting serum. I fear if I apply too much my skin will feel warm or cause a burning sensation as normally retinol do. So far it worked for me. A fine line in my T-zone is slowly disappearing.
Willing buy it again.
Age 60+
Skin Type Combination
Verified Buyer
Using this product for 2weeks. I can see my skin looks so much better.
Fantastic
Verified Reviewer
Reviewed at

This product has helped my skin so much! I do agree there was a learning curve- I tried to use too much product at first and my skin wasn't used to it- I did read the pamphlet & was told to build up the amount & start slow so my fault for using too much. Once I started using a small amount - waiting until absorbed then later applying moisture after- wow! I started getting so many raised spots from sun damage & texture. This has revived my 56 yr old skin- love it!