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Perricone MD Acyl-Glutathione Face%2FEye Duo

Perricone MD

Acyl-Glutathione Face/Eye Duo

Item #: 2259203

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Acyl-Glutathione (pronounced: ay-sil gloo-ta-thigh-on), addresses the accelerated signs of aging, including: severe dryness, extreme loss of elasticity, deep lines and wrinkles, and fragile, thin-looking skin. Used as both a preventative and corrective measure, this treatment helps create visibly more youthful looking skin in just 30 days.

Acyl-Glutathione Eye Lid Serum is scientifically formulated to tighten & firm the upper eye lid area, and also works on tightening the 360 degree orbital rim while smoothing creases and improving the appearance of redness and dark circles. Instantly enhances make-up application by acting as a primer to help make-up glide on more smoothly and improve its wear throughout the day. Light in texture and fast-absorbing with visibly instant tightening and smoothing effects.

Glutathione is the chief, master antioxidant that rapidly depletes with age, stress, the environment and less than optimal health; its replenishment is critical to help skin's defense against accelerated aging. Glutathione deficit shows up on the skin in the way of fatigue, dullness, severe loss of elasticity, deep wrinkles, extreme loss of hydration, visible change in skin texture.

In a 30-day consumer-use study of Acyl-Glutathione, after application every morning and evening:
  • 85% saw a reduction in the appearance of horizontal forehead creases
  • 90% saw a reduction in the appearance of eleven creases
  • 85% saw a reduction in the appearance of smile creases
  • 88% saw a reduction in the appearance of marionette creases
Based on a 4-week (or 30 day) period of use of Acyl-Glutathione Eye Lid Serum:
  • 80% saw improvement in the appearance of dark circles
  • 76% saw improvement in the appearance of creases above their eyes
  • 73% saw improvement in the tightness & firmness of the eye lid skin
  • 73% saw improvement in the redness of their eyelids
  • 76% said their upper eye lids looked smoother
  • 78% agreed this product helped their make-up go on more smoothly
  • 76% agreed this product worked well as a primer to enhance their make-up application and wear
Acyl-Glutathione Face/Eye Duo Includes:
  • Acyl-Glutathione (1.0 oz.)
  • Acyl-Glutathione Eye Lid Serum (0.5 oz.)
Acyl-Glutathione: Dr. Perricone recommends first warming up a small amount of product between your hands to facilitate spread over the entire face. Slide the pads of the fingers from the center of the eyebrows towards the outside of the forehead. Then with the palms of the hand proceed over temples, cheekbones and sides of nose in a gentle patting motion. End by sweeping upwards from the neck to the chin and jawline. Apply morning and evening after make-up removal on well cleansed skin. Optimal results when paired with Cold Plasma.

Acyl-Glutathione Eye Lid Serum: Dr. Perricone recommends applying directly to the eyelid, working up to the brow bone, in gentle patting motions. Apply along the lower contours of the eyes beginning from crows feet and all along under the eyes, also in gently patting motions. Allow serum to absorb for a few moments and follow with an eye cream if extra moisture is needed.
Acyl-Glutathione: Aqua (Water), Isopropyl Palmitate, Tetrahexyldecyl Ascorbate, Cetearyl Alcohol, Phosphatidylcholine, S-Palmitoylglutathione, L-Tyrosine, Dimethyl MEA (DMAE), Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Glycolic Acid, Oligopeptide-17, Oligopeptide-49, Squalane, Butyrospermum Parkii (Shea) Butter, Limnanthes Alba (Meadowfoam) Seed Oil, Docosahexaenoic Acid, Dimethicone, Sesamum Indicum (Sesame) Seed Oil, Glycerin, Magnesium Aspartate, Zinc Gluconate, Phenoxyethanol, Caprylyl Glycol, Parfum (Fragrance), Propylene Glycol, Disodium EDTA, Hydrolyzed Glycosaminoglycans, Elaeis Guineensis (Palm) Oil, Citric Acid, Tocotrienols, Copper Gluconate, Sorbic Acid, Tocopherol, Ascorbyl Palmitate, Thioctic Acid (Alpha-Lipoic Acid), Linalool.

Acyl-Glutathione Eye Lid Serum: Water/Aqua, Pantethine, Avena Sativa (Oat) Kernel Extract, Glycerin, Carbomer, Glycyrrhetinic Acid, S-Palmitoylglutathione, Acetyl Tyrosine, Magnesium Ascorbyl Phosphate, Tetrahexyldecyl Ascorbate, Silica, Xanthan Gum, Dimethyl MEA, Phenoxyethanol, Caprylyl Glycol, Magnesium Silicate, Titanium Dioxide, Magnesium Aspartate, Zinc Gluconate, Sorbic Acid, Hydroxypropyl Cyclodextrin, Fragrance/Parfum, Iron Oxides/CI 77491, Copper Gluconate, Linalool, Sodium Hyaluronate, Citronellol, Acetyl Tetrapeptide-5, Palmitoyl Tripeptide-38.


How to Use+


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Product Reviews


by PowerReviews
Perricone MDAcyl-Glutathione Face/Eye Duo

(based on 6 reviews)


of respondents would recommend this to a friend.


  • Softens skin (3)


No Cons

Best Uses

No Best Uses

Reviewed by 6 customers

Displaying reviews 1-6

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Great Product

By M M

from Seattle

About Me Beauty Conscious


  • Lightweight
  • Moisturizes
  • Non-Greasy
  • Smells Great
  • Softens Skin
  • Soothes Skin


    Best Uses

    • Daily Use
    • Fine Lines/Wrinkles

    Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

    This product works great with continuing use. and skin feels pampered.

    • Skin Type:
    • Dry
    • Age:
    • 60+

    not effective for me

    By DR

    from Chicago

    About Me Minimalist


    • Lightweight


    • Not Effective

    Best Uses

      Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

      I didn't notice any change in my skin from using this product.

      • Skin Type:
      • Combination
      • Age:
      • 45-59

      (4 of 4 customers found this review helpful)


      I love this product. It is definitely worth the price

      By Pilates

      from Wisconsin

      Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

      When I tell people my daughters are 22 and 19 they comment on how I don't look like I could have daughters that age. I've been using these products for years and owe youthful looking skin to them

      • Was this a gift?:
      • No

      (2 of 5 customers found this review helpful)


      Awesome !

      By None

      from Tn

      About Me Budget Buyer

      Verified Buyer


      • Absorbs Quickly
      • Goes On Smoothly
      • Long Lasting
      • Moisturizes Well
      • Not Greasy
      • Smells Great
      • Softens Skin
      • Very Best Results


        Best Uses

        • Bedtime

        Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

        This product does the best .... I will not be without it !

        (19 of 19 customers found this review helpful)


        Great Duo

        By mrsogni

        from Boynton Beach, FL


        • Effective


          Best Uses

            Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

            I've used this duo before, strayed away due to the price and came back because of the results. The eye lid serum is my personal favorite for my 57 year old eyes. The duo is well priced for what you get. Would love a supersize duo!

            • Was this a gift?:
            • No

            (29 of 30 customers found this review helpful)


            UNBELIEVABLE results!!

            By Amy HUGE Perricone Fan

            from Cairns, QLD Australia


            • Hydrates
            • Lifts Eyelids
            • Smoothes skin
            • Softens wrinkles
            • Tightens skin


            • none

            Best Uses

            • Morning and night

            Comments about Perricone MD Acyl-Glutathione Face/Eye Duo:

            I really can't say enough about these two products. I have very fair skin and never really looked after it until i was in my 30's. I use a lot of Perricone products- a big fan of the Cold Plasma range as well- but these two i can't live without! Before Acyl-Glutathione i was really upset at the state of my skin- i felt that i looked older than my age from years of neglect and sun damage, and my eyelids had drooped that much i was contemplating plastic surgery...but not any more! The lines on my forehead and creases in between my brows are getting softer and softer the longer i use the face treatment and the eye serum has my lids back to where they should be! Now i feel like i look younger than my age and people always comment on what good skin i have! I use both products every day under No Foundation Foundation and use them both most nights as well- alternating the face treatment between just on my wrinkles and over my entire face. I am one very happy customer!! Just a note here- although i noticed a difference straight away with these products, after a year the difference is even more pronounced! ♥ Perricone!

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            Product Q&A

            Do you have questions about this product?

            Get answers from in-house experts.

            1 Question | 1 Answer
            Displaying question 1
            • Q:

              With these size bottles; how long should they last?
              Asked on 3/2/2016 by N/A from Colorado

              1 answer

              • Staff Expert


                Acyl-Glutathione (1.0 oz.)
                Acyl-Glutathione Eye Lid Serum (0.5 oz.)

                This set should last 45 days with typical use.

                Answered on 3/7/2016 by Staff Expert from Ulta Beauty
            Displaying question 1

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